CAJ | 학술논문

目的：观察静脉使用小剂量糖皮质激素治疗成人变应性咳嗽的疗效。方法42例变应性咳嗽患者，随机分为观察组和对照组，均给予口服氯雷他定治疗，观察组22例加用小剂量糖皮质激素治疗，连用3 d。在治疗前、治疗后3 d、2周记录患者的咳嗽症状积分及视觉模拟评分(VAS)。结果与治疗前比较，两组治疗后咳嗽症状积分及VAS评分均有下降，差异有统计学意义(P<0.05)，治疗后两组进行组间比较观察组积分下降更显著，差异有统计学意义(P<0.05)。结论小剂量糖皮质激素静脉使用可显著改善变应性咳嗽患者的症状，从而达到更好的治疗目的。
목적：관찰정맥사용소제량당피질격소치료성인변응성해수적료효。방법42례변응성해수환자，수궤분위관찰조화대조조，균급여구복록뢰타정치료，관찰조22례가용소제량당피질격소치료，련용3 d。재치료전、치료후3 d、2주기록환자적해수증상적분급시각모의평분(VAS)。결과여치료전비교，량조치료후해수증상적분급VAS평분균유하강，차이유통계학의의(P<0.05)，치료후량조진행조간비교관찰조적분하강경현저，차이유통계학의의(P<0.05)。결론소제량당피질격소정맥사용가현저개선변응성해수환자적증상，종이체도경호적치료목적。
Objective To observe the curative effect of low-dose intravenous glucocorticoid in the treatment of adult atopic cough. Methods A total of 42 atopic cough patients were randomly divided into observation group and control group. All patients received oral loratadine, while the 22 cases in observation group received additional low dose of glucocorticoid for 3 d. The cough symptom score and visual analogue scale (VAS) before treatment and in 3 d and 2 weeks after treatment were recorded. Results After treatment, the scores of cough symptom and VAS in the two groups were all lower than those before treatment, and the difference had statistical significance (P<0.05). The scores decreased more obviously in the observation group than the control group after treatment, and the difference had statistical significance (P<0.05). Conclusion Treatment of atopic cough with low-dose intravenous glucocorticoid can improve the clinical symptoms significantly in atopic cough patients, and achieve better therapeutic purposes.