CAJ | 학술논문

目的：探讨鼻胆管引流用于预防内镜逆行胰胆管造影术（ERCP）后高淀粉酶血症和胰腺炎的临床效果。方法：将120例拟行 ERCP 的患者随机分为对照组和试验组，每组各60例。对照组患者在 ERCP 后，未给予鼻胆管引流；试验组患者在ERCP 后，给予鼻胆管引流。分别在术后3、12、24 h 测定2组患者血清淀粉酶水平，比较2组患者高淀粉酶血症及胰腺炎的发生率。结果：试验组和对照组患者的性别、年龄等差异均无统计学意义（P ＞0．05）。试验组高淀粉酶血症发生率为10％，显著低于对照组（26．7％），P ＜0．01；试验组胰腺炎发生率为3．33％，显著低于对照组（11．67％），P ＜0．05。试验组术后3、12、24 h血清淀粉酶水平明显低于对照组（P ＜0．05）。结论：ERCP 术后行鼻胆管引流可有效预防高淀粉酶血症及胰腺炎的发生，值得推广。
목적：탐토비담관인류용우예방내경역행이담관조영술（ERCP）후고정분매혈증화이선염적림상효과。방법：장120례의행 ERCP 적환자수궤분위대조조화시험조，매조각60례。대조조환자재 ERCP 후，미급여비담관인류；시험조환자재ERCP 후，급여비담관인류。분별재술후3、12、24 h 측정2조환자혈청정분매수평，비교2조환자고정분매혈증급이선염적발생솔。결과：시험조화대조조환자적성별、년령등차이균무통계학의의（P ＞0．05）。시험조고정분매혈증발생솔위10％，현저저우대조조（26．7％），P ＜0．01；시험조이선염발생솔위3．33％，현저저우대조조（11．67％），P ＜0．05。시험조술후3、12、24 h혈청정분매수평명현저우대조조（P ＜0．05）。결론：ERCP 술후행비담관인류가유효예방고정분매혈증급이선염적발생，치득추엄。
Objective:To observe the clinical effect of endoscopic nasobiliary drainage on the prevention of hyperamylasemia and pancreatitis after endoscopic retrograde cholangiopancreatography(ERCP).Methods:A total of 120 patients who were go-ing to undergo ERCP were selected as the research object and randomly divided into the control group(n=60)and the experi-mental group(n=60).After ERCP,patients in the control group did not receive endoscopic nasobiliary drainage,and patients in the experimental group received endoscopic nasobiliary drainage.At 3,12,24 h after ERCP,the level of serum amylase was detected,and the incidence rates of hyperamylasemia and pancreatitis in the two groups were compared.Results:There was no significant difference in the gender,age,etc.between the experimental group and the control group(P >0.05).The incidence rate of hyperamylasemia in the experimental group was 10%,significantly lower than that in the control group (26.7%),P <0.01.The incidence rate of pancreatitis in the experimental group was 3.33%,significantly lower than that in the control group (11.67%),P <0.05.The levels of serum amylase in the experimental group were significantly lower than that in the control group at 3,12,24 h after ERCP(P <0.05).Conclusions:Endoscopic nasobiliary drainage given after ERCP can effec-tively reduce the incidence rates of hyperamylasemia and pancreatitis.