CAJ | 학술논문

目前中医对于骨髓增生异常综合征的病机基本取得共识，主要责之于“脾、肾”，脾肾亏虚为本，瘀毒阻络为标。根据常见临床表现可将其分为气血两虚证、气阴两虚证、阴虚内热证、阴阳两虚证、瘀毒内阻证等5种证候；中医治疗可与疾病分期相结合，疾病早期以扶助正气为主，在后期加强解毒祛瘀。针对 MDS 的慢性发病过程，充分发挥中医药优势与特色，推广能改善患者临床症状、提高生活质量、延长生存期，延缓白血病转化速度与降低白血病转化率的中药有重要的学术理论价值及广泛的临床应用前景。
목전중의대우골수증생이상종합정적병궤기본취득공식，주요책지우“비、신”，비신우허위본，어독조락위표。근거상견림상표현가장기분위기혈량허증、기음량허증、음허내열증、음양량허증、어독내조증등5충증후；중의치료가여질병분기상결합，질병조기이부조정기위주，재후기가강해독거어。침대 MDS 적만성발병과정，충분발휘중의약우세여특색，추엄능개선환자림상증상、제고생활질량、연장생존기，연완백혈병전화속도여강저백혈병전화솔적중약유중요적학술이론개치급엄범적림상응용전경。
Currently TCMhas basically reached a common view on the pathogenesis mechanism for myelodysplastic syndrome,mainly due to the problems of “spleen and kidney”.Deficiency of spleen and kidney is the fundamental.Etiological factors and pathogenesis is the surface performance.According to the common clinical manifestations,it can be divided into five kinds of syndromes,including the deficiency syndrome of both Qi and blood,deficiency syndrome of both Qi and Yin,syndrome of endogenous heat due to yin deficiency, deficiency syndrome of the Yin and Yang and blood stasis and toxin stasis.TCM can be applied in different stages of diseases,which means to support healthy qi at the early stage of the disease,and to strengthen detoxification and removing stasis later.It has important academic theoretical value and wide prospect of clinical application when giving full play to the advantages and characteristics of Chinese medicine which can improve clinical symptoms,improve life quality,prolong the survival period,slow the speed of leukemic transforma-tion and reduce conversion rate of leukemia according to the chronic pathogenesis of MDS.