医药前沿
醫藥前沿
의약전연
YIAYAO QIANYAN
2014年
22期
109-110
,共2页
西酞普兰%万拉法新%老年抑郁症
西酞普蘭%萬拉法新%老年抑鬱癥
서태보란%만랍법신%노년억욱증
Citalopram%Venlafaxine%Aged depression
目的:探讨西酞普兰与万拉法新治疗老年抑郁症的疗效和安全性。方法将108例老年抑郁症患者随机分为两组,各54例,分别给予西酞普兰和万拉法新治疗,疗程6周,采用汉密尔顿抑郁量表(HAMD)、临床疗效总评量表的病情严重程度(CGI-SI)和副反应量表(TESS)评定疗效和不良反应。结果西酞普兰与万拉法新治疗老年性抑郁症疗效相近,但前者不良反应较后者少而轻微。结论西酞普兰可作为治疗老年抑郁症的首选用药。
目的:探討西酞普蘭與萬拉法新治療老年抑鬱癥的療效和安全性。方法將108例老年抑鬱癥患者隨機分為兩組,各54例,分彆給予西酞普蘭和萬拉法新治療,療程6週,採用漢密爾頓抑鬱量錶(HAMD)、臨床療效總評量錶的病情嚴重程度(CGI-SI)和副反應量錶(TESS)評定療效和不良反應。結果西酞普蘭與萬拉法新治療老年性抑鬱癥療效相近,但前者不良反應較後者少而輕微。結論西酞普蘭可作為治療老年抑鬱癥的首選用藥。
목적:탐토서태보란여만랍법신치료노년억욱증적료효화안전성。방법장108례노년억욱증환자수궤분위량조,각54례,분별급여서태보란화만랍법신치료,료정6주,채용한밀이돈억욱량표(HAMD)、림상료효총평량표적병정엄중정도(CGI-SI)화부반응량표(TESS)평정료효화불량반응。결과서태보란여만랍법신치료노년성억욱증료효상근,단전자불량반응교후자소이경미。결론서태보란가작위치료노년억욱증적수선용약。
Objective To explore the efficacy and side effects of citalopram in the treatment of depression. Methods 108 patients with aged depression were double-blindly assigned to citalopram group and venlafaxine group for 6 weeks. HAMD,CGI and TESS were used to assess the clinical efficacy and side effects. Results Citalopram possessed efficacy similar to venlafaxine. However citalopram had fewer side effects. Conclusion Citalopram may be first drug for treating aged depression.