CAJ | 학술논문

目的：探讨个体化营养支持对心脏直视手术患儿围术期的干预效果。方法选择吉林大学第二医院2005年12月~2014年6月收治的先心病患儿579例为研究对象，年龄为4~36个月。依据围术期营养支持的方法不同将其分为实验组(n=283)与对照组(n=296)，分别采用个体化营养支持法和常规营养支持法。监测两组患儿体重、身高、血清白蛋白的增长以及术后并发症的发生率。结果实验组及对照组患儿体重增加[(3.92±0.76)kg比(1.31±0.48)kg]、身高增长[(2.77±0.72)cm比(1.85±0.69)cm]、血清白蛋白增加量[(5.38±3.14)g/L比(2.11±2.24)g/L]、口腔及肺内感染(2.81%比19.93%)、切口感染率(2.47%比13.18%)以及生理反射延迟发生率(0.35%比3.04%)比较，差异有统计学意义(P<0.05或P<0.01)。实验组患儿的身高、体重及血清白蛋白的增加明显高于对照组，而其口腔、肺内感染以及切口的感染率明显低于对照组。结论个体化营养支持有助于加速围术期患儿组织修复，促进机体功能恢复。
목적：탐토개체화영양지지대심장직시수술환인위술기적간예효과。방법선택길림대학제이의원2005년12월~2014년6월수치적선심병환인579례위연구대상，년령위4~36개월。의거위술기영양지지적방법불동장기분위실험조(n=283)여대조조(n=296)，분별채용개체화영양지지법화상규영양지지법。감측량조환인체중、신고、혈청백단백적증장이급술후병발증적발생솔。결과실험조급대조조환인체중증가[(3.92±0.76)kg비(1.31±0.48)kg]、신고증장[(2.77±0.72)cm비(1.85±0.69)cm]、혈청백단백증가량[(5.38±3.14)g/L비(2.11±2.24)g/L]、구강급폐내감염(2.81%비19.93%)、절구감염솔(2.47%비13.18%)이급생리반사연지발생솔(0.35%비3.04%)비교，차이유통계학의의(P<0.05혹P<0.01)。실험조환인적신고、체중급혈청백단백적증가명현고우대조조，이기구강、폐내감염이급절구적감염솔명현저우대조조。결론개체화영양지지유조우가속위술기환인조직수복，촉진궤체공능회복。
Objective To investigate the effect of the intervention of personalized nutrition support on infants undergo-ing open heart operation during peri-operative period. Methods 579 infants with congenital heart disease from Decem-ber 2005 to June 2014 in the Second Hospital of Jilin University were selected as study objects, they were from 4 months to 36 months old. They were divided into experimental group (n=283) with personalized nutrition support and control group (n=296) with conventional nutrition support according to the different nutritional support method during the perioperative period. The changes of weight, height, serum albumin and the incidence of postoperative complica-tions of two groups were tested and compared. Results Between the experimental group and control group, the increas-ing weight [(3.92±0.76) kg vs (1.31±0.48) kg], increasing height [(2.77±0.72) cm vs (1.85±0.69) cm], serumalbumin [(5.38±3.14) g/L vs (2.11±2.24) g/L], the infection rate of mouth and lungs (2.81% vs 19.93%), the infection rate of in-cision (2.47%v s 13.18%), and physiological reflex retard (0.35%v s 3.04%) had statistically significant differences (P<0.05 or P < 0.01). Increasing height, weight and serum albumin in experimental group were significantly higher than those of the control group, and the infection rate of the mouth, lungs and incision in experimental group were obviously lower than those of the control group. Conclusion Peri-operative personalized nutrition support is helpful to infant with heart disease for accelerating in tissue repair and promoting recovery of body function during operation period.