中国当代医药
中國噹代醫藥
중국당대의약
PERSON
2014年
32期
94-96
,共3页
疏血通%氯吡格雷%急性非ST段抬高心肌梗死%临床效果
疏血通%氯吡格雷%急性非ST段抬高心肌梗死%臨床效果
소혈통%록필격뢰%급성비ST단태고심기경사%림상효과
Shuxuetong%Clopidogrel%Acute non-ST segment elevation myocardial infarction%Clinical effect
目的：研究疏血通注射液辅助氯吡格雷治疗急性非ST段抬高心肌梗死的临床效果。方法选择2009年1月~2014年1月本院收治的70例急性非ST段抬高心肌梗死患者,按照随机数字表法分为试验组和对照组各35例,试验组采用疏血通注射液联合氯吡格雷进行治疗,对照组采用氯吡格雷进行治疗,治疗后1个月,比较两组患者的临床疗效、辅助检查各项参数[左心室舒张末径(LVEDd)、左心室射血分数(LVEF)、ST段降低及缺血导联数]及不良反应发生情况。结果试验组总有效率为97.1%,明显高于对照组的82.9%,差异有统计学意义(χ2=3.9683,P=0.0464)；治疗后,试验组LVEDd、ST段降低及缺血导联数均明显低于对照组,LVEF明显高于对照组(P<0.05)；两组均未发生严重不良反应且经对症治疗后均未造成严重影响。结论疏血通注射液辅助氯吡格雷治疗急性非ST段抬高心肌梗死效果良好,安全性高,值得临床推广应用。
目的：研究疏血通註射液輔助氯吡格雷治療急性非ST段抬高心肌梗死的臨床效果。方法選擇2009年1月~2014年1月本院收治的70例急性非ST段抬高心肌梗死患者,按照隨機數字錶法分為試驗組和對照組各35例,試驗組採用疏血通註射液聯閤氯吡格雷進行治療,對照組採用氯吡格雷進行治療,治療後1箇月,比較兩組患者的臨床療效、輔助檢查各項參數[左心室舒張末徑(LVEDd)、左心室射血分數(LVEF)、ST段降低及缺血導聯數]及不良反應髮生情況。結果試驗組總有效率為97.1%,明顯高于對照組的82.9%,差異有統計學意義(χ2=3.9683,P=0.0464)；治療後,試驗組LVEDd、ST段降低及缺血導聯數均明顯低于對照組,LVEF明顯高于對照組(P<0.05)；兩組均未髮生嚴重不良反應且經對癥治療後均未造成嚴重影響。結論疏血通註射液輔助氯吡格雷治療急性非ST段抬高心肌梗死效果良好,安全性高,值得臨床推廣應用。
목적：연구소혈통주사액보조록필격뢰치료급성비ST단태고심기경사적림상효과。방법선택2009년1월~2014년1월본원수치적70례급성비ST단태고심기경사환자,안조수궤수자표법분위시험조화대조조각35례,시험조채용소혈통주사액연합록필격뢰진행치료,대조조채용록필격뢰진행치료,치료후1개월,비교량조환자적림상료효、보조검사각항삼수[좌심실서장말경(LVEDd)、좌심실사혈분수(LVEF)、ST단강저급결혈도련수]급불량반응발생정황。결과시험조총유효솔위97.1%,명현고우대조조적82.9%,차이유통계학의의(χ2=3.9683,P=0.0464)；치료후,시험조LVEDd、ST단강저급결혈도련수균명현저우대조조,LVEF명현고우대조조(P<0.05)；량조균미발생엄중불량반응차경대증치료후균미조성엄중영향。결론소혈통주사액보조록필격뢰치료급성비ST단태고심기경사효과량호,안전성고,치득림상추엄응용。
Objective To study the clinical efficacy of Shuxuetong injection combined with clopidogrel in the treatment of acute non-ST segment elevation myocardial infarction. Methods 70 cases of patients with acute non-ST segment el-evation myocardial infarction treated in our hospital from January 2009 to January 2014 were selected,and were ran-domly divided into experimental group and control group,35 cases in each group,Shuxuetong injection combined with clopidogrel therapy were given to the experimental group,clopidogrel treatment was given to the control group.After treatment,the efficacy,auxiliary examination parameters [left ventricular end-diastolic diameter (LVEDd),left ventricular ejection fraction (LVEF),ST segment depression and the number of ischemia leads],and adverse reactions of the two groups were analyzed. Results After treatment,the total effective rate of experimental group was 97.1%,higher than 82.9%of the control group,the difference was significant (χ2=3.9683,P=0.0464);LVEDd,ST segment depression and the number of ischemia leads of experimental group was lower than that of the control group respectively,LVEF was higher than that of the control group,the difference was significant (P<0.05);There was no serious adverse reactions in both groups. Conclusion Shuxuetong injection combined with clopidogrel in the treatment of acute non-ST segment eleva-tion myocardial infarction makes good effect,is worthy of clinical application.
