CAJ | 학술논문

目的：探讨抑郁症患者和精神分裂症患者的脑干听觉反应（ ABR）的特点。方法应用NTS-2000型ERP仪及Click短声刺激，测查43例抑郁症（抑郁症组）、43例精神分裂症（精神分裂症组）和50名健康成人对照（对照组）的ABR。结果抑郁症组、精神分裂症组及对照组在绝对潜伏期波Ⅴ（ Pz脑区）、绝对波幅波Ⅲ（ Pz脑区）、波Ⅴ（ Pz脑区）上的差异有显著统计学意义（P均＜0.01）。与对照组和抑郁症组相比，精神分裂症组的绝对潜伏期波Ⅴ（Pz脑区）显著延迟（P均＜0.01），绝对波幅波Ⅲ（ Pz脑区）和绝对波幅波Ⅴ（ Pz脑区）亦显著降低。结论 ABR对临床鉴别抑郁症和精神分裂症有参考价值。
목적：탐토억욱증환자화정신분렬증환자적뇌간은각반응（ ABR）적특점。방법응용NTS-2000형ERP의급Click단성자격，측사43례억욱증（억욱증조）、43례정신분렬증（정신분렬증조）화50명건강성인대조（대조조）적ABR。결과억욱증조、정신분렬증조급대조조재절대잠복기파Ⅴ（ Pz뇌구）、절대파폭파Ⅲ（ Pz뇌구）、파Ⅴ（ Pz뇌구）상적차이유현저통계학의의（P균＜0.01）。여대조조화억욱증조상비，정신분렬증조적절대잠복기파Ⅴ（Pz뇌구）현저연지（P균＜0.01），절대파폭파Ⅲ（ Pz뇌구）화절대파폭파Ⅴ（ Pz뇌구）역현저강저。결론 ABR대림상감별억욱증화정신분렬증유삼고개치。
Objective To investigate the characteristics of auditory brainstem response ( ABR) in patients with depression disorder and schizophrenia . Methods The ABR measurement were carried out in 43 patients with depressive disorders ( the depression group ) , 43 patients with schizophrenias ( the schizophrenia group ) , and 50 normal controls ( the control group ) by using the NTS-2000 type ERP instrument . Results The differences between three groups in the absolute latency wave V ( Pz brain area ) , the absolute amplitude wave Ⅲ ( Pz brain area ) and wave V ( Pz brain area ) were significant ( all P<0.01 ) .Compared with that in the control group and the depression group , the schizophrenia group had significantly delayed the absolute latency wave V ( Pz brain area ) ( all P<0.01 ) as well as significantly decreased absolute wave amplitude Ⅲ( Pz brain area ) and absolute wave Ⅴ( Pz brain area ) . Conclusion ABR is of value for clinical differentiate the depression disorder and schizophrenia .