神经病学与神经康复学杂志
神經病學與神經康複學雜誌
신경병학여신경강복학잡지
JOURNAL OF NEUROLOGY AND NEUROREHABILITATION
2014年
2期
44-47
,共4页
王勤鹰%余敏%顾勤%邓冰%姜嘟嘟%詹青
王勤鷹%餘敏%顧勤%鄧冰%薑嘟嘟%詹青
왕근응%여민%고근%산빙%강도도%첨청
惊厥性癫痫持续状态%老年%病因%治疗
驚厥性癲癇持續狀態%老年%病因%治療
량궐성전간지속상태%노년%병인%치료
convulsive status epilepticus%elderly%etiology%therapy
目的:观察老年惊厥性癫痫持续状态( CSE)的临床特点。方法收集神经重症监护室( NICU)年龄≥60岁的CSE患者28例,回顾性分析其临床特点。结果脑血管病为28例老年CSE的首位病因。接受抗癫痫药物治疗后,CSE症状控制的中位时间为0.9 h,其中16例患者在1 h内症状控制,12例为难治性癫痫持续状态(RSE)。28例患者中,存活16例、死亡12例。死亡者与存活者相比,合并中枢神经系统新发疾病(P=0.027)和RSE的比例显著不同(P=0.027)。结论老年CSE患者基础情况差,病因多样,合并有中枢神经系统新发疾病或有RSE者的死亡率高。
目的:觀察老年驚厥性癲癇持續狀態( CSE)的臨床特點。方法收集神經重癥鑑護室( NICU)年齡≥60歲的CSE患者28例,迴顧性分析其臨床特點。結果腦血管病為28例老年CSE的首位病因。接受抗癲癇藥物治療後,CSE癥狀控製的中位時間為0.9 h,其中16例患者在1 h內癥狀控製,12例為難治性癲癇持續狀態(RSE)。28例患者中,存活16例、死亡12例。死亡者與存活者相比,閤併中樞神經繫統新髮疾病(P=0.027)和RSE的比例顯著不同(P=0.027)。結論老年CSE患者基礎情況差,病因多樣,閤併有中樞神經繫統新髮疾病或有RSE者的死亡率高。
목적:관찰노년량궐성전간지속상태( CSE)적림상특점。방법수집신경중증감호실( NICU)년령≥60세적CSE환자28례,회고성분석기림상특점。결과뇌혈관병위28례노년CSE적수위병인。접수항전간약물치료후,CSE증상공제적중위시간위0.9 h,기중16례환자재1 h내증상공제,12례위난치성전간지속상태(RSE)。28례환자중,존활16례、사망12례。사망자여존활자상비,합병중추신경계통신발질병(P=0.027)화RSE적비례현저불동(P=0.027)。결론노년CSE환자기출정황차,병인다양,합병유중추신경계통신발질병혹유RSE자적사망솔고。
Objective To observe the clinical characteristics of elderly patients with convulsive status epilepticus (CSE). Methods Retrospectively analyzed the clinical characteristics of 28 aged patients (age above 60) with CSE admitted to our neurological intensive care unit ( NICU) . Results The most common etiology of CSE in elder patients was cerebrovascular disease .Median time from antiepileptic drugs ( AEDs ) treatment to CSE successful terminated was 0.9 hour.Among these patients, CSE was terminated successfully in 16 patients within 1 hour, while other 12 patients were in status of refractory status epilepticus (RSE).As a result, 16 patients survived and 12 died. Compared died patients with those survived , the rates of new-onset central nervous system lesions ( P=0.027 ) and RSE ( P=0.027 ) were significantly different . Conclusion The elderly patients with CSE have poor health basis and various etiologies of CSE .Presenting of new-onset of central nervous system lesions and RSE are associated with the increased rate of death .