CAJ | 학술논문

为了提高玉米蛋白的骨诱导性和骨结合性，以促进其在骨组织工程领域中的应用，将玉米蛋白多孔支架材料浸泡于5倍模拟体液（5×SBF）中，尝试在不同的条件下对玉米蛋白多孔支架材料表面进行仿生矿化。通过场发射扫描电镜（ SEM）观察仿生矿化后多孔支架材料各个表面的形貌，能谱（ EDS）计算出钙磷比（ Ca/P）比。在5倍模拟体液中浸泡后，材料各表面均形成了分布和尺寸相对均匀的微米级（2～10 um）颗粒。其钙磷比接近羟基磷灰石，可以认为获得了比较理想的玉米蛋白－羟基磷灰石多孔支架复合材料。
위료제고옥미단백적골유도성화골결합성，이촉진기재골조직공정영역중적응용，장옥미단백다공지가재료침포우5배모의체액（5×SBF）중，상시재불동적조건하대옥미단백다공지가재료표면진행방생광화。통과장발사소묘전경（ SEM）관찰방생광화후다공지가재료각개표면적형모，능보（ EDS）계산출개린비（ Ca/P）비。재5배모의체액중침포후，재료각표면균형성료분포화척촌상대균균적미미급（2～10 um）과립。기개린비접근간기린회석，가이인위획득료비교이상적옥미단백－간기린회석다공지가복합재료。
In order to promote the application in bone tissue engineering, the zein scaffold was soaked in a solution of 5 times the concentration of simulated body fluid (5 ×SBF) to enhance its bone inductivity and osseointegration.The field emission scanning elec-tron microscopy (SEM) was employed to observe the surface microstructures of the coating and energy dispersive spectrometer (EDS) which was attached to the SEM was used to carry out the elemental analysis and to calculate the ratio of calcium to phosphorus ( Ca/P) .The surface of the composite materials form uniform micro particles(2-10 um) that the ratio of calcium to phosphorus closed to that of hydroxyapatite (HA) after soaked in 5SBF.The zein-HA composite can be considered as an ideal material in bone tissue engi-neering.