CAJ | 학술논문

目的：探讨芬吗通联合坤泰胶囊治疗卵巢功能低下(decreasing ovarian reserve，DOR)的临床效果及促排卵后的受孕情况。方法选取2012年1月～2013年7月收治的57例DOR患者，芬吗通联合坤泰胶囊治疗3个月，检测卵泡刺激素(FSH)、促黄体生成素(LH)、雌二醇(E 2)、抗苗勒管激素(AMH)、窦卵泡数、卵巢体积、动脉收缩期峰值流速(PSV)。治疗前后采用自身对照。结果 FSH、LH水平较治疗前下降，E 2、AMH、窦卵泡数、PSV水平较治疗前上升，差异有统计学意义（P＜0.05），卵巢体积较治疗前增加，但差异无统计学意义。联合治疗后给予来曲唑促排卵受孕率提高。结论芬吗通联合坤泰胶囊治疗卵巢功能低下，可有效改善卵巢储备，加以促排卵治疗，提高DOR患者的受孕成功率。
목적：탐토분마통연합곤태효낭치료란소공능저하(decreasing ovarian reserve，DOR)적림상효과급촉배란후적수잉정황。방법선취2012년1월～2013년7월수치적57례DOR환자，분마통연합곤태효낭치료3개월，검측란포자격소(FSH)、촉황체생성소(LH)、자이순(E 2)、항묘륵관격소(AMH)、두란포수、란소체적、동맥수축기봉치류속(PSV)。치료전후채용자신대조。결과 FSH、LH수평교치료전하강，E 2、AMH、두란포수、PSV수평교치료전상승，차이유통계학의의（P＜0.05），란소체적교치료전증가，단차이무통계학의의。연합치료후급여래곡서촉배란수잉솔제고。결론분마통연합곤태효낭치료란소공능저하，가유효개선란소저비，가이촉배란치료，제고DOR환자적수잉성공솔。
Objective Research the clinical effect of Femoston combined with kuntai capsule on decreasing ovarian reserve(DOR),and the conception situation after ovarian induction .Methods Select 57 cases from patients with DOR, after the treatment of Femoston combined with kuntai capsule for 3 months, test FSH、LH、E 2、AMH、antral follicles、ovarian volume and PSV,pre and post treatment used self-control. Results The FSH level and LH level were decreased before treatment,E 2、AMH、antral follicles、and PSV level were increased, the difference was significant (P<0.05).Ovarian volume was added,but the difference was not significant. After treatment of letrozole in ovulation induction, the pregnancy rata was improved.Conclusion The treatment of DOR with Femoston combined with kuntai capsule,could improve the ovarian reserve effectively. Combined with the treatment of ovarian induction , it could improve pregnancy rata in DOR women.