CAJ | 학술논문

目的：探讨手术治疗部分性癫痫患儿的远期疗效。方法回顾性分析2005年6月至2008年6月在斯坦伦布什大学泰格堡儿童医院该院接受外科手术治疗的158例部分性癫痫患儿的临床资料，观察患儿术后生活质量、智商改善及癫痫控制情况，并对影响手术远期疗效的相关因素进行分析。结果术后对患儿随访5年，158例患儿术后1、3、5年癫痫控制率分别为100．00％、94．85％、94．35％，其中MRI结果及病程是影响癫痫控制率的独立危险因素。智商1、3、5年改善率分别为89．87％、89．71％、88．71％，其中病程、手术年龄是影响患儿智商改善效果的独立危险因素。术后1、3、5年生活质量改善率分别为93．04％、91．18％、90．32％，其中术前智商、手术方式是影响患儿术后生活质量的独立危险因素。结论尽早对患儿实施手术，改善患儿病灶范围，能有效控制癫痫发作，改善患儿智商水平，提高患儿术后生活质量。
목적：탐토수술치료부분성전간환인적원기료효。방법회고성분석2005년6월지2008년6월재사탄륜포십대학태격보인동의원해원접수외과수술치료적158례부분성전간환인적림상자료，관찰환인술후생활질량、지상개선급전간공제정황，병대영향수술원기료효적상관인소진행분석。결과술후대환인수방5년，158례환인술후1、3、5년전간공제솔분별위100．00％、94．85％、94．35％，기중MRI결과급병정시영향전간공제솔적독립위험인소。지상1、3、5년개선솔분별위89．87％、89．71％、88．71％，기중병정、수술년령시영향환인지상개선효과적독립위험인소。술후1、3、5년생활질량개선솔분별위93．04％、91．18％、90．32％，기중술전지상、수술방식시영향환인술후생활질량적독립위험인소。결론진조대환인실시수술，개선환인병조범위，능유효공제전간발작，개선환인지상수평，제고환인술후생활질량。
Objective To investigate the long‐term effect of surgical treatment of partial seizures in children .Methods The au‐thor was studying in the University of Stellenbosch ,Tygerberg Children′s Hospital .The clinical data of 158 children with partial seizures selected from June 2005 to June 2008 were retrospective analyzed .The postoperative quality of life ,improvement of IQ and the situation of seizure control ,and affect long‐term efficacy of surgery‐related factors were analyzed .Results The patients were followed up for 5 years .The control rate of seizures of 1 ,3 ,5 years were 100 .00% ,94 .85% ,94 .35% ,MRI findings and the course were control independent risk factors affecting the rate of seizure .The rates of IQ improvement of 1 ,3 ,5 years were 89 .87% , 89 .71% ,88 .71% ,of which preoperative IQ ,disease duration ,age at surgery in children were independent risk factors affecting IQ improvement .life .Quality improvement rate of 1 ,3 ,5 years were 93 .04% ,91 .18% ,90 .32% ,and IQ preoperative ,operative ap‐proach were independent risk factors affecting the quality of life postoperatively .Conclusion The surgery operating as soon as pos‐sible could be better for children to improve the range of lesions ,and also could effectively control seizures ,improving the level of intelligence in children and the quality of life postoperatively .