CAJ | 학술논문

目的：调查了解西安地区骨质疏松症患者体内维生素D 水平的状况。方法随机选取2012年12月－2013年11月我科440例骨质疏松症患者，采集其清晨空腹静脉血，用Cobase 6000型电化学发光仪（瑞士罗氏诊断）检测血中25（OH）D的水平，按照2012年12月－2013年5月为冬春季和2013年6月－2013年11月为夏秋季进行分组，用SPSS13．0软件进行数据分析。结果共调查了440例骨质疏松症患者，其中女性患者数量远大于男性患者，这些患者普遍存在着维生素D水平不足现象，其中维生素D严重缺乏和缺乏所占比例较大，男女两组在年龄和血清25（ OH） D水平上均无统计学差异，而且冬春季患者体内维生素D的水平要低于夏秋季的患者。结论本研究显示西安地区骨质疏松症患者维生素D不足现象比较普遍，男性女性之间无明显差别，而且体内维生素D水平与季节的变化有关，为骨质疏松症的防治提供一定的数据参考。
목적：조사료해서안지구골질소송증환자체내유생소D 수평적상황。방법수궤선취2012년12월－2013년11월아과440례골질소송증환자，채집기청신공복정맥혈，용Cobase 6000형전화학발광의（서사라씨진단）검측혈중25（OH）D적수평，안조2012년12월－2013년5월위동춘계화2013년6월－2013년11월위하추계진행분조，용SPSS13．0연건진행수거분석。결과공조사료440례골질소송증환자，기중녀성환자수량원대우남성환자，저사환자보편존재착유생소D수평불족현상，기중유생소D엄중결핍화결핍소점비례교대，남녀량조재년령화혈청25（ OH） D수평상균무통계학차이，이차동춘계환자체내유생소D적수평요저우하추계적환자。결론본연구현시서안지구골질소송증환자유생소D불족현상비교보편，남성녀성지간무명현차별，이차체내유생소D수평여계절적변화유관，위골질소송증적방치제공일정적수거삼고。
Objective To investigate the serum 25-hydroxyvitamin D status of patients with osteoporosis in Xi′an.Methods Four hundred and forty osteoporotic patients were randomly selected from December in 2012 to November in 2013 in Xian.Fasting blood samples were collected.Serum 25-hydroxyvitamin D was determined using electrochemiluminescence ( Rocher, Swiss ) . These patients were divided in the winter-spring group ( from December 2012 to May 2013) and summer-autumn group ( from June 2013 to November 2013).The data were analyzed using a SPSS13.0 software.Results Four hundred and forty osteoporotic patients were investigated, in which female patients were much more than male ones.Vitamin D inadequacy existed generally in osteoporotic patients.Among them, vitamin D deficiency and critical deficiency were in a greater ratio.There was no statistic difference in the level of vitamin D between the male and the female.Vitamin D level in osteoporotic patients in winter-spring group was lower than that in patients, in summer-autumn group.Conclusion The study shows that the prevalence of vitamin D deficiency in osteoporotic patients in Xi′an was common.No difference exists between males and females.The vitamin D level is associated with the change of the season.This study provides certain reference for the prevention and treatment of osteoporosis.