CAJ | 학술논문

目的：探讨护理干预对艾滋病（ AIDS ）患者治疗依从性及外周血CD 4＋T淋巴细胞水平、病毒载量的影响。方法：选择符合标准的患者30例，随机分为观察组和对照组各15例，对照组实施常规护理，观察组实施护理干预，比较两组患者治疗依从性、外周血CD 4＋T淋巴细胞水平及病毒载量。结果：观察组患者完全依从12例、基本依从2例和不依从1例，对照组患者完全依从7例、基本依从5例和不依从3例，差异有统计学意义（ P＜0．05）。两组患者入组时外周血CD4＋T淋巴细胞计数相似，差异无统计学意义（ P＞0．05）；治疗3个月、6个月两组患者外周血CD4＋T淋巴细胞计数较治疗前均提高（P＜0．05），但是观察组升高幅度更大（P＜0．05）。观察组患者全血病毒载量抑制明显优于对照组，差异有统计学意义（ P＜0．05）。结论：护理干预能有效提高AIDS患者的治疗依从性，提高外周血CD4＋T细胞水平，协助控制病毒载量。
목적：탐토호리간예대애자병（ AIDS ）환자치료의종성급외주혈CD 4＋T림파세포수평、병독재량적영향。방법：선택부합표준적환자30례，수궤분위관찰조화대조조각15례，대조조실시상규호리，관찰조실시호리간예，비교량조환자치료의종성、외주혈CD 4＋T림파세포수평급병독재량。결과：관찰조환자완전의종12례、기본의종2례화불의종1례，대조조환자완전의종7례、기본의종5례화불의종3례，차이유통계학의의（ P＜0．05）。량조환자입조시외주혈CD4＋T림파세포계수상사，차이무통계학의의（ P＞0．05）；치료3개월、6개월량조환자외주혈CD4＋T림파세포계수교치료전균제고（P＜0．05），단시관찰조승고폭도경대（P＜0．05）。관찰조환자전혈병독재량억제명현우우대조조，차이유통계학의의（ P＜0．05）。결론：호리간예능유효제고AIDS환자적치료의종성，제고외주혈CD4＋T세포수평，협조공제병독재량。
Objective:To investigate the effect of nursing intervention on the CD 4+T cell level and viral load in the peripheral blood and compliance with therapy in acquired immunodeficiency syndrome ( AIDS ) patients.Method:30 eligible patients were selected and randomly divided into observation group and control group, 15 patients in each group;the control group used usual care , while the observation group used nurs-ing intervention , and the CD 4+T cell levels and viral loads in the peripheral bloods and compliances with the therapies in the patients of the two groups were compared .Result:Of the patients in the observation group , 12 cases were completely compliant with the therapy , 2 cases basically compliant with the therapy and 1 in-compliant with the therapy;while the patients in the control group , 7 cases were completely compliant with the therapy, 5 cases basically compliant with the therapy and 3 cases incompliant with the therapy;and the difference was statistically significant (P<0.05).The CD4+T lymphocyte counts in the peripheral bloods of the patients of the two groups when entering the groups were similar , and the difference was statistically in-significant (P>0.05);3 months and 6 months after the therapies, the CD4+T lymphocyte counts in the pe-ripheral bloods of the patients of the two groups were both increased ( P<0.05) , but the increasing extents of the observation group were greater ( P<0.05) .The inhibition of viral load in the whole blood in the patients of the observation group was significantly better than that of the control group , and the difference was statisti-cally significant ( P<0.05) .Conclusion:Nursing intervention can effectively elevate the compliance with the therapy and the CD 4+T cell level in the peripheral blood and is helpful to control the viral load in AIDS pa-tients.