CAJ | 학술논문

目的：分析结核性脑膜炎临床及脑脊液特征。方法：回顾性分析49例结核性脑膜炎患者的临床资料，按照临床特征将所有患者分为Ⅰ组（脑神经麻痹，29例）和Ⅱ组（无脑神经麻痹，20例），比较分析两组患者的脑脊液常规及生化特征。结果：Ⅰ组CT扫描异常率为96.6%，略高于Ⅱ组的90.0%，但组间差异无统计学意义（ P>0.05）；Ⅰ组患者脑脊液蛋白含量明显高于Ⅱ组，两组间差异有统计学意义（ P<0.05）；Ⅰ组患者脑脊液中IgG、IgM、Alb含量与Ⅱ组比较，差异均有统计学意义（ P<0.05）。结论：结核性脑膜炎常伴有脑神经损害，临床医师应熟练掌握该疾病的临床及脑脊液特征，及早诊治，改善患者预后。
목적：분석결핵성뇌막염림상급뇌척액특정。방법：회고성분석49례결핵성뇌막염환자적림상자료，안조림상특정장소유환자분위Ⅰ조（뇌신경마비，29례）화Ⅱ조（무뇌신경마비，20례），비교분석량조환자적뇌척액상규급생화특정。결과：Ⅰ조CT소묘이상솔위96.6%，략고우Ⅱ조적90.0%，단조간차이무통계학의의（ P>0.05）；Ⅰ조환자뇌척액단백함량명현고우Ⅱ조，량조간차이유통계학의의（ P<0.05）；Ⅰ조환자뇌척액중IgG、IgM、Alb함량여Ⅱ조비교，차이균유통계학의의（ P<0.05）。결론：결핵성뇌막염상반유뇌신경손해，림상의사응숙련장악해질병적림상급뇌척액특정，급조진치，개선환자예후。
Objective To analyze the clinical and cerebrospinal fluid characteristics of 49 cases with tuberculous meningi-tis. Method The clinical data of 49 cases with tuberculous meningitis was retrospectively analyzed,the patients were divided into groupⅠ( cranial nerve palsy,29 cases)and groupⅡ( no cranial nerve palsy,20 cases)according to clinical characteristics,in the two groups,the conventional and biochemical characteristics of cerebrospinal fluid were compared and analyzed. Results The abnormal rate of CT scan in group Ⅰ was 96. 6%,It was slightly higher than 90. 0% of groupⅡ,but there was no significant difference between groups(P>0. 05);the protein content of cerebrospinal fluid in group Ⅰ was significantly higher than group Ⅱ,the difference was statistically significant be-tween the two groups(P<0. 05);the IgG,IgM,Alb content of cerebrospinal fluid in group Ⅰcompared to group Ⅱ,the differences were statistically significant( P<0. 05). Conclusion Tuberculous meningitis is often cocurrent with cranial nerve palsy,clinicians should be fa-miliar with the clinical and cerebrospinal fluid characteristics of the disease,early diagnosis and treatment,improve the prognosis of pa-tients.