中国临床保健杂志
中國臨床保健雜誌
중국림상보건잡지
CHINESE JOURNAL OF CLINICAL HEALTHCARE
2014年
6期
561-563
,共3页
王吉%王浩%秦爱梅%朱兵%杜凯音%苑学愚%付思齐%王津%孙洪良%胡智%骆雷鸣
王吉%王浩%秦愛梅%硃兵%杜凱音%苑學愚%付思齊%王津%孫洪良%鬍智%駱雷鳴
왕길%왕호%진애매%주병%두개음%원학우%부사제%왕진%손홍량%호지%락뢰명
血压%昼夜节律%脑梗死%肥大,左心室%动脉粥样硬化%老年人
血壓%晝夜節律%腦梗死%肥大,左心室%動脈粥樣硬化%老年人
혈압%주야절률%뇌경사%비대,좌심실%동맥죽양경화%노년인
Blood pressure%Circadian rhythm%Brain infarction%Hypertrophy,left ventricular%Atherosclerosis%Aged
目的：探讨老年原发性高血压患者不同形态血压晨峰（MBPS）对脑梗死（CI）、左心室肥厚（LVH）以及对颈动脉内膜增厚（IMT）的影响。方法对320例老年原发性高血压患者进行24 h 动态血压监测（ABPM）、头颅 CT、头颅 MR、头颅 DSA 和超声心动图检查以及颈动脉超声，将 MBPS 值≥35 mm Hg 的119例患者入选为 MBPS 研究对象，根据其血压形态，分为勺型晨峰组76例（超勺型7例及勺型69例）、非勺型晨峰组43例（反勺型3例及非勺型40例），分别对各组患者的血脂、血糖等生化指标，以及脑梗死、左室肥厚、双侧颈动脉内膜等进行分析。结果（1）勺型晨峰组与非勺型晨峰组之间的临床指标组间差异无统计学意义（P ＞0．05）；（2）非勺型晨峰组脑梗死发病率、左心室肥厚检出率、颈动脉内膜增厚检出率高于勺型晨峰组（P ＜0．05）。结论老年性高血压非勺型血压晨峰患者脑梗死发生率明显高于勺型血压晨峰患者，更易引起左室肥厚和颈动脉硬化。
目的：探討老年原髮性高血壓患者不同形態血壓晨峰（MBPS）對腦梗死（CI）、左心室肥厚（LVH）以及對頸動脈內膜增厚（IMT）的影響。方法對320例老年原髮性高血壓患者進行24 h 動態血壓鑑測（ABPM）、頭顱 CT、頭顱 MR、頭顱 DSA 和超聲心動圖檢查以及頸動脈超聲，將 MBPS 值≥35 mm Hg 的119例患者入選為 MBPS 研究對象，根據其血壓形態，分為勺型晨峰組76例（超勺型7例及勺型69例）、非勺型晨峰組43例（反勺型3例及非勺型40例），分彆對各組患者的血脂、血糖等生化指標，以及腦梗死、左室肥厚、雙側頸動脈內膜等進行分析。結果（1）勺型晨峰組與非勺型晨峰組之間的臨床指標組間差異無統計學意義（P ＞0．05）；（2）非勺型晨峰組腦梗死髮病率、左心室肥厚檢齣率、頸動脈內膜增厚檢齣率高于勺型晨峰組（P ＜0．05）。結論老年性高血壓非勺型血壓晨峰患者腦梗死髮生率明顯高于勺型血壓晨峰患者，更易引起左室肥厚和頸動脈硬化。
목적：탐토노년원발성고혈압환자불동형태혈압신봉（MBPS）대뇌경사（CI）、좌심실비후（LVH）이급대경동맥내막증후（IMT）적영향。방법대320례노년원발성고혈압환자진행24 h 동태혈압감측（ABPM）、두로 CT、두로 MR、두로 DSA 화초성심동도검사이급경동맥초성，장 MBPS 치≥35 mm Hg 적119례환자입선위 MBPS 연구대상，근거기혈압형태，분위작형신봉조76례（초작형7례급작형69례）、비작형신봉조43례（반작형3례급비작형40례），분별대각조환자적혈지、혈당등생화지표，이급뇌경사、좌실비후、쌍측경동맥내막등진행분석。결과（1）작형신봉조여비작형신봉조지간적림상지표조간차이무통계학의의（P ＞0．05）；（2）비작형신봉조뇌경사발병솔、좌심실비후검출솔、경동맥내막증후검출솔고우작형신봉조（P ＜0．05）。결론노년성고혈압비작형혈압신봉환자뇌경사발생솔명현고우작형혈압신봉환자，경역인기좌실비후화경동맥경화。
Objective To investigate the influence of different types of morning blood pressure surge(MBPS) on the cerebral infarction h(CI),left ventricular hypertrophy (LVH)and carotid intima-media thickness(IMT)in elder-ly patients with essential hypertension.Methods A total of 320 elderly hypertension patients underwent 24-hour ambula-tory blood pressure monitoring (ABPM),brain CT or MRI or cerebral digital subtraction angiography (DSA)and echocar-diography and carotid arteries ultrasound examination.According to the value of MBPS(MBPS≥35 mm Hg),119 patients were selected as the MBPS group,and the blood pressure types were dertermined.The patients were divided into 2 groups:dipper MBPS group (76 patients:7 patients with extreme-dipper and 69 patients with dipper)and non-dipper MBPS group (43 patients:3 patients with reverse-dipper and 40 patients with non-dipper).The level of blood lipid,blood sugar and oth-er biochemical indicators,as well as single and double side carotid intima-media thickness,left ventricular hypertrophy were tested and analyzed.Results (1 )There were no significant differences in clinical manifestations between non-dip-per MBPS group and non-dipper MBPS group(P >0.05).(2)In non-dipper MBPS group,the level of cerebral infarction, LVH and IMT were higher than those in dipper MBPS(P <0.05).Conclusion Non-dipper MBPS is related to the CI, LVH and IMT in the elderly hypertensive patients.
