CAJ | 학술논문

目的：探讨分析实验室采用间接免疫荧光法和免疫印迹法检测ANA和ANAs的结果及价值。方法：对2317例自身抗体受检者的年龄、性别及ANA和ANAs检测结果进行分析。结果：在2317例受检者中，ANA和／或ANAs阳性914例（39．4％），女性占77．7％，男性占22．3％，36岁及以上年龄段，女性占50．1％，男性的占16．1％；A N A阳性740例（31．9％），ANAs阳性723例（31．2％），ANA 和 ANAs 均阳性549例，ANA （＋）和 ANAs （＋）符合率74.2％，ANA（－）和ANAs（－）符合率89．0％，总体符合率84．2％。结论：联合检测ANA和ANAs ，不仅可以减低假阴性率和假阳性率，而且能为诊断和鉴别诊断自身免疫病提供更有力的实验室依据。
목적：탐토분석실험실채용간접면역형광법화면역인적법검측ANA화ANAs적결과급개치。방법：대2317례자신항체수검자적년령、성별급ANA화ANAs검측결과진행분석。결과：재2317례수검자중，ANA화／혹ANAs양성914례（39．4％），녀성점77．7％，남성점22．3％，36세급이상년령단，녀성점50．1％，남성적점16．1％；A N A양성740례（31．9％），ANAs양성723례（31．2％），ANA 화 ANAs 균양성549례，ANA （＋）화 ANAs （＋）부합솔74.2％，ANA（－）화ANAs（－）부합솔89．0％，총체부합솔84．2％。결론：연합검측ANA화ANAs ，불부가이감저가음성솔화가양성솔，이차능위진단화감별진단자신면역병제공경유력적실험실의거。
Objective :To explore the value and results that using indirect immunofluorescence and immunoblottingto detect ANA and ANAs .Methods :Analysis the 2 317 cases were grouped by age ,sex and the results of ANA and AN‐As .Results:In this 2 317 cases ,the positive of ANA and/or ANAs were 914 cases (39 .4% ) ,women accounted for 77.7% ,males accounted for 22 .3% ,36 years and over age group ,women accounted for 50 .1% ,accounting for 16 .1%of men;ANA positive 740 cases (31 .9% ) ,ANAs tested positive for 723 cases (31 .2% ) ,ANA and ANAs were posi‐tive in 549 cases ,ANA (+ ) and ANAs (+ ) in line with the rate of 74 .2% ,ANA (-) and ANAs (-) compliance rate of 89 .0% ,the overall compliance rate of 84 .2% .Conclusion:Combined detection of ANA and ANAs ,not only can reduce the false‐negative and false‐positive rate ,but also provide the basis for more effective laboratory diagnosis and differential diagnosis of autoimmune disease .