中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2014年
24期
64-66
,共3页
电化学发光免疫分析检测%乙型病毒性肝炎%透明质酸酶%血管紧张素Ⅱ%肝纤维化
電化學髮光免疫分析檢測%乙型病毒性肝炎%透明質痠酶%血管緊張素Ⅱ%肝纖維化
전화학발광면역분석검측%을형병독성간염%투명질산매%혈관긴장소Ⅱ%간섬유화
Electrochemiluminescence immunoassay%Hepatitis B%Hyaluronidase%AngiotensinⅡ%Liver fibrosis
目的：通过电化学发光免疫分析检测，探讨乙型病毒性肝炎（以下简称乙肝）患者的血清血管紧张素Ⅱ（AngⅡ）与透明质酸酶（HA）之间的关系。方法选取2012年1月至2014年1月高密市人民医院检验科收治的乙肝患者100例，其中急性乙肝患者50例（急性组），慢性乙肝患者50例（慢性组），选择同期在我院体检的健康人群50例作为对照组。采用速率法检测血清 AngⅡ水平，电化学发光法检测 HA 水平，对三组的结果进行统计分析。结果慢性组血清 AngⅡ和 HA 水平明显高于急性组和对照组，急性组明显高于对照组，差异有统计学意义（t =1.306、2.839、1.804，P 均<0.05）；Pearson 相关系数分析显示：血清 AngⅡ和 HA 水平呈正相关（r =0.703，P <0.05）。结论乙肝患者血清 AngⅡ和 HA 水平关系密切，两者均可作为判断肝纤维化程度的重要指标。
目的：通過電化學髮光免疫分析檢測，探討乙型病毒性肝炎（以下簡稱乙肝）患者的血清血管緊張素Ⅱ（AngⅡ）與透明質痠酶（HA）之間的關繫。方法選取2012年1月至2014年1月高密市人民醫院檢驗科收治的乙肝患者100例，其中急性乙肝患者50例（急性組），慢性乙肝患者50例（慢性組），選擇同期在我院體檢的健康人群50例作為對照組。採用速率法檢測血清 AngⅡ水平，電化學髮光法檢測 HA 水平，對三組的結果進行統計分析。結果慢性組血清 AngⅡ和 HA 水平明顯高于急性組和對照組，急性組明顯高于對照組，差異有統計學意義（t =1.306、2.839、1.804，P 均<0.05）；Pearson 相關繫數分析顯示：血清 AngⅡ和 HA 水平呈正相關（r =0.703，P <0.05）。結論乙肝患者血清 AngⅡ和 HA 水平關繫密切，兩者均可作為判斷肝纖維化程度的重要指標。
목적：통과전화학발광면역분석검측，탐토을형병독성간염（이하간칭을간）환자적혈청혈관긴장소Ⅱ（AngⅡ）여투명질산매（HA）지간적관계。방법선취2012년1월지2014년1월고밀시인민의원검험과수치적을간환자100례，기중급성을간환자50례（급성조），만성을간환자50례（만성조），선택동기재아원체검적건강인군50례작위대조조。채용속솔법검측혈청 AngⅡ수평，전화학발광법검측 HA 수평，대삼조적결과진행통계분석。결과만성조혈청 AngⅡ화 HA 수평명현고우급성조화대조조，급성조명현고우대조조，차이유통계학의의（t =1.306、2.839、1.804，P 균<0.05）；Pearson 상관계수분석현시：혈청 AngⅡ화 HA 수평정정상관（r =0.703，P <0.05）。결론을간환자혈청 AngⅡ화 HA 수평관계밀절，량자균가작위판단간섬유화정도적중요지표。
Objective To investigate the correlation of serum angiotensin Ⅱ(Ang Ⅱ)and hy-aluronidase(HA)level of patients with hepatitis B by electrochemiluminescence immunoassay. Methods One hundred patients with hepatitis B from January 2012 to January 2014 were selected,including 50 pa-tients with acute hepatitis B(acute group)and 50 patients with chronic hepatitis B(chronic group), 50 healthy people in same period were selected as control group. Using the rate method to detect serum Ang Ⅱ level,using electrochemical luminescence method to detect the serum HA levels,the results of three groups were analyzed. Results The serum Ang Ⅱ and HA levels of the chronic group were obvi-ously higher than those of the acute group and the control group,that of acute group was significantly higher than that of the control group,the differences were significant(t = 1. 306,2. 839,1. 804,P <0. 05);Pearson correlation analysis showed that the serum Ang Ⅱ and HA levels were positively correla-ted(r = 0. 703,P < 0. 05). Conclusions The levels of serum Ang Ⅱ is closely correlated with the lev-el of HA in patients with hepatitis B. Both of them are important indexes to evaluate the degree of liver fibrosis.
