CAJ | 학술논문

目的：观察中西药结合治疗早期先兆流产合并宫内积血临床疗效。方法将80例患者按随机数字表法分为对照组和观察组各40例。观察组给予补肾、健脾开胃的中药。每天1剂，每剂500 mL，分2次服用。两组均采用地屈孕酮片，起始剂量1次口服4片地屈孕酮，每片10 mg。随后每隔8小时服用1片地屈孕酮，直到阴道流血症状停止。两组患者均接受维生素E每天2次，每次100 mg。叶酸每天2次，每次5 mg。比较两组临床疗效和不良反应。结果对照组痊愈9例，显效为10例，有效有10例，无效11例，总有效率为72．5％；观察组痊愈10例，显效10例，有效17例，无效3例，总有效率92．5％。观察组总有效率优于对照组（χ2＝5．54，P＜0．05）。相比治疗前，两组宫内积血面积都减少（t＝4．32、6．21，均P＜0．05）；观察组宫内积血面积改善情况优于对照组（ t＝1．54，P＜0．05）。结论采用补肾、健脾开胃中药联合西药治疗早期先兆流产合并宫内积血可以提高总有效率，无不良反应。该方案值得临床进一步研究和使用。
목적：관찰중서약결합치료조기선조유산합병궁내적혈림상료효。방법장80례환자안수궤수자표법분위대조조화관찰조각40례。관찰조급여보신、건비개위적중약。매천1제，매제500 mL，분2차복용。량조균채용지굴잉동편，기시제량1차구복4편지굴잉동，매편10 mg。수후매격8소시복용1편지굴잉동，직도음도류혈증상정지。량조환자균접수유생소E매천2차，매차100 mg。협산매천2차，매차5 mg。비교량조림상료효화불량반응。결과대조조전유9례，현효위10례，유효유10례，무효11례，총유효솔위72．5％；관찰조전유10례，현효10례，유효17례，무효3례，총유효솔92．5％。관찰조총유효솔우우대조조（χ2＝5．54，P＜0．05）。상비치료전，량조궁내적혈면적도감소（t＝4．32、6．21，균P＜0．05）；관찰조궁내적혈면적개선정황우우대조조（ t＝1．54，P＜0．05）。결론채용보신、건비개위중약연합서약치료조기선조유산합병궁내적혈가이제고총유효솔，무불량반응。해방안치득림상진일보연구화사용。
Objective To observe the clinical efficacy of traditional Chinese medicine dialectical therapy and Western medicine in the treatment of the threatened abortion with intrauterine blood.Methods 80 patients were divided into the control group and observation group randomly according to digital table method.There were 40 cases in each group.The observation group was given medicine of improving the function of kidney,spleen and stomach.This medicine was taken for twice a day of 500mL.The patients in the two groups were taken dydrogesterone tablets.An oral starting dose of 4 dydrogesterone tablets was given.Each tablets content 10mg drugs.Then dydrogesterone was taken every 8 hours till symptoms of vaginal bleeding stopped.The patients in the two groups took 100mg vitamin E twice a day.5mg folic acid was taken twice daily.The clinical efficacy and adverse reactions were studied and compared.Results In the control group,9 patients healed.10 cases showed markedly effective.10 cases had effect. 11 cases showed no effect.The total effective rate was 72.5%.In the observation group,10 cases were cured.10 cases showed markedly effective.17 cases had effect.3 cases had no effect.The total effective rate was 92.5%.The total effective rate in the observation group was better than that of the control group (χ2 =5.54,P<0.05).Compared with prior treatment, hemorrhage area were deduced in the two groups ( t =1.54, P <0.05 ) .After treatment, the hemorrhage area in the two groups had significant difference(t =4.32,6.21,all P <0.05).Conclusion The Chinese medicine and Western medicine on the treatment of threatened abortion intrauterine hematoma showed higher total efficiency rate and had no adverse reactions.The clinical program was worth of further study and use.