吉林医学
吉林醫學
길림의학
JILIN MEDICAL JOURANL
2014年
35期
7788-7789
,共2页
帕洛诺司琼%肺癌%化疗%疗效
帕洛諾司瓊%肺癌%化療%療效
파락낙사경%폐암%화료%료효
Palonosetron%Lung cancer%Chemotherapy%Effect
目的：探析帕洛诺司琼预防肺癌化疗中恶心、呕吐的效果。方法：随机选择晚期肺癌化疗患者40例，分为观察组与对照组。观察患者化疗中急性呕吐反应、延迟呕吐的情况、恶心分级情况及改善不良反应。结果：观察组患者急性呕吐与对照组差异无统计学意义（P＞0.05）；延迟呕吐情况、患者恶心控制情况，观察组均显著高于对照组。观察组不良反应发生率较对照组低，差异无统计学意义（P＞0.05）。结论：晚期肺癌的化疗中，帕洛诺司琼在延迟呕吐的止吐方面及患者恶心控制方面较阿扎司琼疗效好，在急性呕吐止吐方面作用与阿扎司琼相似，临床不良反应轻微，值得推广应用。
目的：探析帕洛諾司瓊預防肺癌化療中噁心、嘔吐的效果。方法：隨機選擇晚期肺癌化療患者40例，分為觀察組與對照組。觀察患者化療中急性嘔吐反應、延遲嘔吐的情況、噁心分級情況及改善不良反應。結果：觀察組患者急性嘔吐與對照組差異無統計學意義（P＞0.05）；延遲嘔吐情況、患者噁心控製情況，觀察組均顯著高于對照組。觀察組不良反應髮生率較對照組低，差異無統計學意義（P＞0.05）。結論：晚期肺癌的化療中，帕洛諾司瓊在延遲嘔吐的止吐方麵及患者噁心控製方麵較阿扎司瓊療效好，在急性嘔吐止吐方麵作用與阿扎司瓊相似，臨床不良反應輕微，值得推廣應用。
목적：탐석파락낙사경예방폐암화료중악심、구토적효과。방법：수궤선택만기폐암화료환자40례，분위관찰조여대조조。관찰환자화료중급성구토반응、연지구토적정황、악심분급정황급개선불량반응。결과：관찰조환자급성구토여대조조차이무통계학의의（P＞0.05）；연지구토정황、환자악심공제정황，관찰조균현저고우대조조。관찰조불량반응발생솔교대조조저，차이무통계학의의（P＞0.05）。결론：만기폐암적화료중，파락낙사경재연지구토적지토방면급환자악심공제방면교아찰사경료효호，재급성구토지토방면작용여아찰사경상사，림상불량반응경미，치득추엄응용。
Objective To explore the effect of palonosetron prevent nausea and vomiting in lung cancer chemotherapy.Methods Randomly selected 40 advanced lung cancer chemotherapy patients.divided them into observation group and control group.observed patients with acute vomiting response,vomiting of delay. the nausea classification in two groups、suspend the vomiting prevention of adverse reactions.Results The observation group of patients with acute vomiting and control group had no significant difference(P>0.05);delayed vomiting, nausea and control patients,the observation group were significantly higher than those of control group.The adverse reaction in observation group was lower than that in the control group,no significant difference(P>0.05).Conclusion In late lung cancer chemotherapy,the curative effect of palonosetron patients with delayed anti-nausea aspects of vomiting,nausea control is better than Aza SiQiong,has the similar effect of the aspect of acute vomiting anti-nausea to Aza SiQiong,little clinical adverse reaction,it is worthy of popularization application.
