CAJ | 학술논문

目的：观察CO2激光联合护理治疗肛管尖锐湿疣的临床疗效。方法：将78例肛管尖锐湿疣患者随机分为治疗组与对照组，每组39例，治疗组接受CO2激光联合护理治疗，1次/周，连续2～3次；对照组接受CO2激光治疗，1次/周，连续2～3次。末次治疗后第1周进行疗效评价，第4周、第8周和第12周观察复发率。治疗前及末次治疗后1周进行实验室检查，并观察不良反应。结果：在末次治疗后1周，治疗组和对照组疣体清除率分别为97.44%和94.87%（P＞0.05）。治疗组治疗后总复发率（17.95%）明显低于对照组（41.3%）（P=0.025）。治疗组及对照组均未发生严重的不良反应，主要的不良反应包括红斑、疼痛、溃疡和疤痕等。结论：CO2激光联合护理治疗肛管尖锐湿疣的治愈率高，复发率低，安全性好。
목적：관찰CO2격광연합호리치료항관첨예습우적림상료효。방법：장78례항관첨예습우환자수궤분위치료조여대조조，매조39례，치료조접수CO2격광연합호리치료，1차/주，련속2～3차；대조조접수CO2격광치료，1차/주，련속2～3차。말차치료후제1주진행료효평개，제4주、제8주화제12주관찰복발솔。치료전급말차치료후1주진행실험실검사，병관찰불량반응。결과：재말차치료후1주，치료조화대조조우체청제솔분별위97.44%화94.87%（P＞0.05）。치료조치료후총복발솔（17.95%）명현저우대조조（41.3%）（P=0.025）。치료조급대조조균미발생엄중적불량반응，주요적불량반응포괄홍반、동통、궤양화파흔등。결론：CO2격광연합호리치료항관첨예습우적치유솔고，복발솔저，안전성호。
Objective To investigate the safety and efficacy of carbon dioxide laser combined with nursing in the treatment of anal tube condyloma acuminatum.Methods Seventy-eight patients with anal tube condyloma acuminatum were randomly assigned to the treatment group and control group in an allocation ratio of 1:1.The treatment group was treated with carbon dioxide laser combined with nursing weekly for 2 to 3 times.The control group was treated with carbon dioxide laser weekly for 2 to 3 times.The recurrence rate was evaluated at weeks 4,8,and l2 after the treatment ended.Results At l week after the last treatment 97.44%and 94.87%of the base line warts were eliminated in the treatment group and the control group respectively(P>0.05).The overall recurrence rate of the treatment group was significantly lower than that in the control group(17.95%Vs 41.3%,P=0.025).There was no severe adverse event in either group.The main adverse event were mild symptoms including erythema,pain,ulcer and scarring.Conclusion Our Results confirmed that carbon dioxide laser combined with nursing is an effective,safe and well-tolerated treatment for anal tube condylomata acuminata.