CAJ | 학술논문

光敏剂产生单线态氧的能力是评价其光动力活性的因素之一。采用2,5-二甲基呋喃为吸收剂,通过高效液相色谱法研究了1-3代硝基芳基苄醚树枝配体轴向取代酞菁硅（Ⅳ）单线态氧的生成速率、生成速率常数及量子产率。结果表明,轴向取代酞菁硅（Ⅳ）单线态氧的生成速率和生成速率常数均随着树枝代数的增加而逐渐增大,低代的树枝配体轴向取代酞菁硅（Ⅳ）的单线态氧量子产率较高,这可能与不同代树枝配体对酞菁核的位点分离有关。研究将为开发轴向取代酞菁硅（Ⅳ）配合物作为新型光敏剂提供重要的理论参考。
광민제산생단선태양적능력시평개기광동력활성적인소지일。채용2,5-이갑기부남위흡수제,통과고효액상색보법연구료1-3대초기방기변미수지배체축향취대태정규（Ⅳ）단선태양적생성속솔、생성속솔상수급양자산솔。결과표명,축향취대태정규（Ⅳ）단선태양적생성속솔화생성속솔상수균수착수지대수적증가이축점증대,저대적수지배체축향취대태정규（Ⅳ）적단선태양양자산솔교고,저가능여불동대수지배체대태정핵적위점분리유관。연구장위개발축향취대태정규（Ⅳ）배합물작위신형광민제제공중요적이론삼고。
The singlet oxygen(102) production capabilitity of photosensitizers is an important factor to assess their potential as effective photodynamic therapy(PDT) agents. In this paper, the 102 production rate, produc- tion rate constant and quantum yield of silicon(IV) phthalocyanine axially bearing 1-3rd generations poly(nitro aryl benzyl ether) dendritic substituents were evaluated by a high performance liquid chromatographic method. The results show that the 1O2 production rate and production rate constant of these compounds increase gradu- ally with dendritic generations increase. And the 102 quantum yield of silicon(IV) phthalocyanine with 1St gen- eration dendritic ligand was the highest. This may be due to the isolation effect of the dendritic ligands on the phthalocyanine core. The parameters of the observed 102 production properties will provide valuable data for these dendrimer phthalocyanines as promising photosensitizer in PDT application.