米卡芬净多学科临床应用评价
미잡분정다학과림상응용평개
  • 万方数据
    中国临床药理学杂志 중국림상약이학잡지
    THE CHINESE JOURNAL OF CLINICAL PHARMACOLOGY
    2014年 11期 1071-1078 ,共8页

    陈德昌%冯四洲%胡建达%黄晓军%金有豫%康焰%李建国%李若瑜%李玉珍%刘开彦%刘又宁%马麟麟%马晓春%马小军%梅丹%邱海波%石炳毅%孙爱宁%孙春华%孙利华%孙丽莹%孙铁英%万献尧%王椿%王贵强%王辉%王明贵%王汝龙%王睿%王育琴%翁心华%吴久鸿%肖永红%徐英春%翟所迪%赵志刚%周新%朱利平

    진덕창%풍사주%호건체%황효군%금유예%강염%리건국%리약유%리옥진%류개언%류우저%마린린%마효춘%마소군%매단%구해파%석병의%손애저%손춘화%손리화%손려형%손철영%만헌요%왕춘%왕귀강%왕휘%왕명귀%왕여룡%왕예%왕육금%옹심화%오구홍%초영홍%서영춘%적소적%조지강%주신%주리평

    注射用米卡芬净钠%侵袭性真菌病%念珠菌%曲霉菌 註射用米卡芬淨鈉%侵襲性真菌病%唸珠菌%麯黴菌
    주사용미잡분정납%침습성진균병%념주균%곡매균
    micafungin sodium for injection%invasive fungal disease%candidiasis%aspergillus
    本文参考国内外侵袭性真菌病诊疗领域多学科专家对米卡芬净的基础及临床应用的多项研究和指南推荐，以其作用机制、体外抗菌活性、对生物膜的作用及耐药性、药代动力学为基础，参考其在血液病／血液恶性肿瘤、重症、实体器官移植、呼吸和感染等侵袭性真菌病患者所在临床科室的防治策略和临床应用经验进行全面的评价；同时，对其药物经济学也进行了介绍。
    본문삼고국내외침습성진균병진료영역다학과전가대미잡분정적기출급림상응용적다항연구화지남추천，이기작용궤제、체외항균활성、대생물막적작용급내약성、약대동역학위기출，삼고기재혈액병／혈액악성종류、중증、실체기관이식、호흡화감염등침습성진균병환자소재림상과실적방치책략화림상응용경험진행전면적평개；동시，대기약물경제학야진행료개소。
    This paper made reference to various studies on the basis and clinical application of micafungin at home and abroad performed by multi-discipline experts on the treatment of invasive fungal diseases and guid-ance recommended.Based on micafungin ’ s mechanism, antibacterial activity in vitro, functions on biofilm and drug resistance as well as its pharmacokinetic study, this paper comprehensively evaluated the clinical application experience and relevant prevention and treatment strategies for invasive fungal diseases, such as hematological disease or malignancies, severe illness, solid organ transplantation, respiratory and other infections.At the same time, the pharmacoeconomics of micafungin was introduced.
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