中国临床药理学杂志
中國臨床藥理學雜誌
중국림상약이학잡지
THE CHINESE JOURNAL OF CLINICAL PHARMACOLOGY
2014年
11期
1048-1050
,共3页
沃泰西汀%抗抑郁剂%5-羟色胺再摄取抑制剂%临床药理学%临床评价%安全性
沃泰西汀%抗抑鬱劑%5-羥色胺再攝取抑製劑%臨床藥理學%臨床評價%安全性
옥태서정%항억욱제%5-간색알재섭취억제제%림상약이학%림상평개%안전성
vortioxetin%antidepressant%5 -hydroxytryptamine re -uptake inhibitor%clinical pharmacology%clinical evaluation%safety
沃泰西汀是一种新型抗抑郁药,其作用机制主要与抑制5-羟色胺的再摄取、增强中枢神经系统5-羟色胺的活性有关,主要用于治疗抑郁症,其安全性和耐受性较好。本文对沃泰西汀的临床药理学、临床评价和安全性等进行介绍。
沃泰西汀是一種新型抗抑鬱藥,其作用機製主要與抑製5-羥色胺的再攝取、增彊中樞神經繫統5-羥色胺的活性有關,主要用于治療抑鬱癥,其安全性和耐受性較好。本文對沃泰西汀的臨床藥理學、臨床評價和安全性等進行介紹。
옥태서정시일충신형항억욱약,기작용궤제주요여억제5-간색알적재섭취、증강중추신경계통5-간색알적활성유관,주요용우치료억욱증,기안전성화내수성교호。본문대옥태서정적림상약이학、림상평개화안전성등진행개소。
Vortioxetine is a novel antidepressant.The mechanism of the antidepressant effect is related with its enhancement of serotonergic activi-ty in the central nervous system through inhibition of the re-uptake of serotonin (5-HT).Vortioxetine is clinically applied for the treatment of major depression, safe and well tolerated.This article reviews the clinical pharmacology, clinical evaluation and safety of vortioxetin.