CAJ | 학술논문

角膜新生淋巴管构成了角膜免疫反应的传入弧，在免疫反应中发挥了重要作用。由于新生淋巴管的出现破坏了免疫机制使角膜移植术后排斥反应发生率升高。随着淋巴管内皮标记物的相继出现和对淋巴管生成因子的研究深入，众多学者对角膜淋巴管在角膜免疫排斥反应机制、治疗和预防等方面进行了大量研究，通过抑制新生淋巴管提高植片存活率。
각막신생림파관구성료각막면역반응적전입호，재면역반응중발휘료중요작용。유우신생림파관적출현파배료면역궤제사각막이식술후배척반응발생솔승고。수착림파관내피표기물적상계출현화대림파관생성인자적연구심입，음다학자대각막림파관재각막면역배척반응궤제、치료화예방등방면진행료대량연구，통과억제신생림파관제고식편존활솔。
Corneal newborn lymphatic vessels construct the afferent arc of corneal immunological reaction, which play important role in immune response. The corneal transplantation rejection rate rises due to the emergence of new lymphatic vessel which breaks the immunologic mechanism. With the founding of specific marker of lymphatic endothelial cells and research advancing of growth factor of lymphatic vessels, the mechanism, therapy and prevention of corneal immunological rejection reaction of corneal lymphatic vessel have been studied intensively. The graft survival rate has been greatly improved through inhibiting newborn lymphatic vessel.