CAJ | 학술논문

目的：探讨甲状腺功能检测在不孕女性诊治过程中的临床实用价值。方法采用电化学发光免疫技术，分别检测160例不孕女性（不孕组）和160例健康体检女性（健康对照组）的血清促甲状腺激素（TSH）、游离三碘甲状腺原氨酸（FT3）、游离甲状腺素（FT4）、三碘甲状腺原氨酸（T3）、甲状腺素（T4）、抗甲状腺过氧化物酶抗体（TPOAb）和抗甲状腺球蛋白抗体（TGAb）水平，并进行比较分析。结果不孕组女性TSH、TPOAb、TGAb水平明显高于对照组，而T3水平明显低于对照组，差异有统计学意义（P＜0．05）；不孕组TSH、T3、TPOAb和TGAb的阳性率分别为20．63％、16．25％、17．50％和15．63％，对照组阳性率分别为5．63％、2．50％、5．00％和3．75％，不孕组阳性率明显高于对照组，差异有统计学意义（P＜0．05）。结论甲状腺功能异常与不孕症有密切的关系。
목적：탐토갑상선공능검측재불잉녀성진치과정중적림상실용개치。방법채용전화학발광면역기술，분별검측160례불잉녀성（불잉조）화160례건강체검녀성（건강대조조）적혈청촉갑상선격소（TSH）、유리삼전갑상선원안산（FT3）、유리갑상선소（FT4）、삼전갑상선원안산（T3）、갑상선소（T4）、항갑상선과양화물매항체（TPOAb）화항갑상선구단백항체（TGAb）수평，병진행비교분석。결과불잉조녀성TSH、TPOAb、TGAb수평명현고우대조조，이T3수평명현저우대조조，차이유통계학의의（P＜0．05）；불잉조TSH、T3、TPOAb화TGAb적양성솔분별위20．63％、16．25％、17．50％화15．63％，대조조양성솔분별위5．63％、2．50％、5．00％화3．75％，불잉조양성솔명현고우대조조，차이유통계학의의（P＜0．05）。결론갑상선공능이상여불잉증유밀절적관계。
Objective To explore clinical value of thyroid function test in the diagnosis and treatment of female infertility. Methods Serum levels of thyroid stimulating hormone(TSH) ,free triiodothyronine(FT3) ,free thyroxine (FT4) ,triiodothyronine(T3) ,thyroxine(T4) ,anti‐thyroid peroxidase antibody(TPOAb) and antithyroglobulin anti‐body (TGAb) were detected by electrochemiluminescence immunoassay technology in 160 infertile women (infertility group) and 160 healthy cases (control group). Results Serum levels of TSH ,TPOAb and TGAb in infertility group were significantly higher than those in control group(P<0. 05) ,while the serum T3 level in infertility group was sig‐nificantly lower than that in control group(P<0. 05). The positive rate of TSH ,T3 ,TPOAb and TGAb in infertility group were 20. 63% ,16. 25% ,17. 50% and 15. 63% ,which were significantly higher than those in the control group (5. 63% ,2. 50% ,5. 00% and 3. 75% ,P<0. 05). Conclusion Thyroid dysfunction could be closely related to female infertility.