CAJ | 학술논문

目的：调查常州市2011—2013年甲状腺癌发病和死亡情况，了解其分布特征及规律。方法从常州市肿瘤登记处和常州市疾病预防控制中心居民死因监测登记报告信息系统中提取常州市2011—2013年甲状腺癌新发病例数据和甲状腺癌死亡病例数据。2011—2013年报告甲状腺癌新发病例847例，计算甲状腺癌发病率、粗发病率、标化发病率、死亡率、粗死亡率、标化死亡率。结果847例患者中男145例、女702例，男女发病比例为1：4.84，男女粗发病率比为1：4.82，差异有统计学意义（χ2=53.89，P<0.05）。常州市2011—2013年甲状腺癌发病情况显示：粗发病率从2011年的5.57/10万上升到2013年的10.23/10万，标化发病率从2011年的4.46/10万上升至2013年的8.07/10万，发病顺位从第13位上升到第8位。女性报告粗发病率从2011年的9.14/10万上升到2013年的17.20/10万，标化发病率从2011年的7.30/10万上升至2013年的13.30/10万，发病顺位从第8位上升到第6位；男性报告粗发病率3年间变化不大，发病顺位均在第14位。2011—2013年甲状腺癌标化死亡率分别为0.29/10万、0.23/10万、0.29/10万，3年间常州市甲状腺癌的死亡率无明显波动。男女死亡率比为1：1.86，差异无统计学意义（χ2=3.54，P>0.05）。经病理学诊断的808例甲状腺癌患者中，627例（77.6%）为乳头状癌，140例（17.3%）为滤泡癌，18例（2.2%）为髓样癌，16例（2.0%）为未分化癌，7例（0.9%）为其他类型癌。结论2011—2013年常州市甲状腺癌发病率逐年上升，女性更为明显，而死亡率无明显波动，可为政府部门制订肿瘤防治对策提供参考依据。
목적：조사상주시2011—2013년갑상선암발병화사망정황，료해기분포특정급규률。방법종상주시종류등기처화상주시질병예방공제중심거민사인감측등기보고신식계통중제취상주시2011—2013년갑상선암신발병례수거화갑상선암사망병례수거。2011—2013년보고갑상선암신발병례847례，계산갑상선암발병솔、조발병솔、표화발병솔、사망솔、조사망솔、표화사망솔。결과847례환자중남145례、녀702례，남녀발병비례위1：4.84，남녀조발병솔비위1：4.82，차이유통계학의의（χ2=53.89，P<0.05）。상주시2011—2013년갑상선암발병정황현시：조발병솔종2011년적5.57/10만상승도2013년적10.23/10만，표화발병솔종2011년적4.46/10만상승지2013년적8.07/10만，발병순위종제13위상승도제8위。녀성보고조발병솔종2011년적9.14/10만상승도2013년적17.20/10만，표화발병솔종2011년적7.30/10만상승지2013년적13.30/10만，발병순위종제8위상승도제6위；남성보고조발병솔3년간변화불대，발병순위균재제14위。2011—2013년갑상선암표화사망솔분별위0.29/10만、0.23/10만、0.29/10만，3년간상주시갑상선암적사망솔무명현파동。남녀사망솔비위1：1.86，차이무통계학의의（χ2=3.54，P>0.05）。경병이학진단적808례갑상선암환자중，627례（77.6%）위유두상암，140례（17.3%）위려포암，18례（2.2%）위수양암，16례（2.0%）위미분화암，7례（0.9%）위기타류형암。결론2011—2013년상주시갑상선암발병솔축년상승，녀성경위명현，이사망솔무명현파동，가위정부부문제정종류방치대책제공삼고의거。
Objective To investigate the morbidity and mortality of thyroid cancer in Changzhou during 2011 -2013 and learn its distribution characteristic and regularity. Methods Thyroid cancer incidence data and death data in Changzhou during 2011-2013 were extracted from Changzhou cancer registry and the death cause surveillance and report information system of disease prevention and control centre in Changzhou. 847 new cases were reported during 2011-2013. The incidence,crude and standardized incidence,mortality,crude and standardized mortality were calculated. Results 847 new cases including 145 males and 702 females,the ratio of mortality was 1:4. 84,the ratio of crude mortality was 1:4. 82 and the difference was signifi-cant(χ2 =53. 89,P<0. 05). The morbidity of thyroid cancer in Changzhou from 2011 to 2013 showed that the crude mortality increased from 5. 57/100 000 in 2011 to 10. 23/100 000 in 2013 and the standardized incidence increased from 4. 46/100 000 to 8. 07/100 000 in 2013. Incidence rate ranked 13th in 2011,while it ranked 8th. Among females,incidence rate of thyroid cancer increased from 9. 14/100 000 in 2011 to 17. 20/100 000 in 2013 and the standardized incidence increased from 7. 30/100 000 in 2011 to 13. 30/100 000 in 2013. Incidence rate ranked 8th in 2011,while it ranked 6th. Among males,incidence rate of thyroid cancer still ranked 14th with little change in the three years. Standardized death rate was 0. 29/100 000 in 2011, 0. 23/100 000 in 2012 and 0. 29/100 000 in 2013 with little change in the three years. The death rate between males and females was1:1. 86,without significant difference(χ2 =3. 54,P>0. 05). Among the 808 cases confirmed as thyroid caner by patho-logical diagnosis,627(77. 6%)were papillary carcinoma,140(17. 3%)were follicular carcinoma,18(2. 2%)were me-dullary carcinoma,16(2. 0%)were undifferentiated carcinoma and 7(0. 9%)were other types. Conclusion Thyroid canc-er incidence is increasing sharply in Changzhou city,especially among females,while the mortality has no obvious change. The result provides reference for the government to work out the cancer preventive strategies.