医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2014年
36期
315-315
,共1页
坎地沙坦CHF%CRP水平
坎地沙坦CHF%CRP水平
감지사탄CHF%CRP수평
Candesartan%CHF%CRP level
目的调查坎地沙坦对未服用ACEI的CHF患者血清CRP水平的影响,探讨其抑制炎症反应,保护心脏的效果。方法选择我院未服用ACEI的慢性心衰住院患者200例,研究采用未服用ACEI的CHF患者随机分为对照组和干预组,干预药物采用坎地沙坦8mg/d,分别对入组时、2个月及6个月时均测量血清CRP水平。结果血清CRP水平在干预组低于对照组,差别有统计学意义(<0.05),干预组中6个月水平低于2个月水平,差别有统计学意义(<0.05)。结论坎地沙坦降低未服用ACEI的CHF患者血浆CRP水平,存在抑制炎症作用,长期口服坎地沙坦可以改善心室重构,保护心脏。
目的調查坎地沙坦對未服用ACEI的CHF患者血清CRP水平的影響,探討其抑製炎癥反應,保護心髒的效果。方法選擇我院未服用ACEI的慢性心衰住院患者200例,研究採用未服用ACEI的CHF患者隨機分為對照組和榦預組,榦預藥物採用坎地沙坦8mg/d,分彆對入組時、2箇月及6箇月時均測量血清CRP水平。結果血清CRP水平在榦預組低于對照組,差彆有統計學意義(<0.05),榦預組中6箇月水平低于2箇月水平,差彆有統計學意義(<0.05)。結論坎地沙坦降低未服用ACEI的CHF患者血漿CRP水平,存在抑製炎癥作用,長期口服坎地沙坦可以改善心室重構,保護心髒。
목적조사감지사탄대미복용ACEI적CHF환자혈청CRP수평적영향,탐토기억제염증반응,보호심장적효과。방법선택아원미복용ACEI적만성심쇠주원환자200례,연구채용미복용ACEI적CHF환자수궤분위대조조화간예조,간예약물채용감지사탄8mg/d,분별대입조시、2개월급6개월시균측량혈청CRP수평。결과혈청CRP수평재간예조저우대조조,차별유통계학의의(<0.05),간예조중6개월수평저우2개월수평,차별유통계학의의(<0.05)。결론감지사탄강저미복용ACEI적CHF환자혈장CRP수평,존재억제염증작용,장기구복감지사탄가이개선심실중구,보호심장。
Objective To investigate the ef ect of candesartan on not taking ACEI CHF serum level of CRP,discusses its inhibiting the inflammatory reaction,heart protective ef ect.Methods In our hospital not taking ACEI 200 in chronic heart failure patients,the patients with CHF were randomly divided not taking ACEI into intervention group and control group,drug intervention by candesartan 8mg/d,respectively in two groups,2 months and 6 months were measured the serum level of CRP.Results The serum level of CRP in the intervention group was lower than the control group,the dif erence was significant ( <0.05),the intervention group 6 months level of less than 2 months,the dif erence was significant ( <0.05).Conclusion Candesartan reduced the plasma CHF CRP levels in patients with non ACEI users,there are anti-inflammatory,long-term oral candesartan can improve left ventricular remodeling,protect the heart.