中国医师杂志
中國醫師雜誌
중국의사잡지
JOURNAL OF CHINESE PHYSICIAN
2013年
11期
1470-1473
,共4页
普查%视网膜病,早产儿%眼底%婴儿,新生
普查%視網膜病,早產兒%眼底%嬰兒,新生
보사%시망막병,조산인%안저%영인,신생
Mass screening%Retinopathy of prematurity%Fundus oculi%Infant,newborn
目的 RetcamⅢ筛查婴幼儿眼底病变,将结果中早产儿视网膜病变(retinopathy ofprematurity,ROP)的发病率及相关影响因素进行分析.方法 选取从2012年5月至2013年4月间就诊于温州医科大学附属第二医院&育英儿童医院的婴幼儿共1097例,门诊筛查的婴幼儿333例(设为Ⅰ组),新生儿科住院筛查的早产儿共764例(设为Ⅱ组),将眼底筛查结果记录,并将ROP与胎数、出生体重、孕周、性别、新生儿呼吸窘迫综合征(neonatal respiratory distress syndrome,NRDS)、新生儿窒息、新生儿高胆红素血症、颅内出血、先天性心脏病、动脉导管未闭(patent ductus arteriosus,PDA)、新生儿贫血、新生儿败血症、支气管肺发育不良(bronchopulmonary dysplasia,BPD)、新生儿小肠结肠炎(necrotizing enterocolitis,NEC)等疾病进行spearman相关性分析.结果 Ⅱ组中ROP有98例,发病率为12.8％.胎数、出生体重、孕周与ROP显著相关(P＜0.05),ROP与NRDS、新生儿窒息、颅内出血、新生儿贫血、败血症、BPD及NEC呈显著相关(P＜0.05),与PDA、新生儿高胆红素血症、先天性心脏病无相关性(P＞0.05).结论 RetcamⅢ是检测婴幼儿眼底病变的重要手段,而ROP仍是早产儿最常见的眼病,温州地区ROP发病率为12.83％,胎数、出生体重、孕周、NRDS、新生儿窒息、颅内出血、新生儿贫血、败血症、BPD及NEC是ROP的重要影响因素.
目的 RetcamⅢ篩查嬰幼兒眼底病變,將結果中早產兒視網膜病變(retinopathy ofprematurity,ROP)的髮病率及相關影響因素進行分析.方法 選取從2012年5月至2013年4月間就診于溫州醫科大學附屬第二醫院&育英兒童醫院的嬰幼兒共1097例,門診篩查的嬰幼兒333例(設為Ⅰ組),新生兒科住院篩查的早產兒共764例(設為Ⅱ組),將眼底篩查結果記錄,併將ROP與胎數、齣生體重、孕週、性彆、新生兒呼吸窘迫綜閤徵(neonatal respiratory distress syndrome,NRDS)、新生兒窒息、新生兒高膽紅素血癥、顱內齣血、先天性心髒病、動脈導管未閉(patent ductus arteriosus,PDA)、新生兒貧血、新生兒敗血癥、支氣管肺髮育不良(bronchopulmonary dysplasia,BPD)、新生兒小腸結腸炎(necrotizing enterocolitis,NEC)等疾病進行spearman相關性分析.結果 Ⅱ組中ROP有98例,髮病率為12.8％.胎數、齣生體重、孕週與ROP顯著相關(P＜0.05),ROP與NRDS、新生兒窒息、顱內齣血、新生兒貧血、敗血癥、BPD及NEC呈顯著相關(P＜0.05),與PDA、新生兒高膽紅素血癥、先天性心髒病無相關性(P＞0.05).結論 RetcamⅢ是檢測嬰幼兒眼底病變的重要手段,而ROP仍是早產兒最常見的眼病,溫州地區ROP髮病率為12.83％,胎數、齣生體重、孕週、NRDS、新生兒窒息、顱內齣血、新生兒貧血、敗血癥、BPD及NEC是ROP的重要影響因素.
목적 RetcamⅢ사사영유인안저병변,장결과중조산인시망막병변(retinopathy ofprematurity,ROP)적발병솔급상관영향인소진행분석.방법 선취종2012년5월지2013년4월간취진우온주의과대학부속제이의원&육영인동의원적영유인공1097례,문진사사적영유인333례(설위Ⅰ조),신생인과주원사사적조산인공764례(설위Ⅱ조),장안저사사결과기록,병장ROP여태수、출생체중、잉주、성별、신생인호흡군박종합정(neonatal respiratory distress syndrome,NRDS)、신생인질식、신생인고담홍소혈증、로내출혈、선천성심장병、동맥도관미폐(patent ductus arteriosus,PDA)、신생인빈혈、신생인패혈증、지기관폐발육불량(bronchopulmonary dysplasia,BPD)、신생인소장결장염(necrotizing enterocolitis,NEC)등질병진행spearman상관성분석.결과 Ⅱ조중ROP유98례,발병솔위12.8％.태수、출생체중、잉주여ROP현저상관(P＜0.05),ROP여NRDS、신생인질식、로내출혈、신생인빈혈、패혈증、BPD급NEC정현저상관(P＜0.05),여PDA、신생인고담홍소혈증、선천성심장병무상관성(P＞0.05).결론 RetcamⅢ시검측영유인안저병변적중요수단,이ROP잉시조산인최상견적안병,온주지구ROP발병솔위12.83％,태수、출생체중、잉주、NRDS、신생인질식、로내출혈、신생인빈혈、패혈증、BPD급NEC시ROP적중요영향인소.
Objective To investigate incidence and severity of retinopathy of prematurity (ROP)screened by RetcamⅢ and the related factors.Comparative case series were designed.Methods A study was performed among infants who required screening by RetcamⅢ in the second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University,and carried out between May 2012 and April 2013.A total of 1097 infants met the study criteria,and were divided into group Ⅰ (n =333 from outpatient screening) and group Ⅱ (n =764 from inpatient screening).Variables were recorded,including birth weight (BW),gestational age (GA),number of births (NOB,singleton/twins/triplets),gender,neonatal respiratory distress syndrome (NRDS),patent ductus arteriosus (PDA),neonatal asphyxia,neonatal hyperbilirubinemia,intracranial hemorrhage,congenital heart disease,neonatal anemia,neonatal sepsis,necrotizing enterocolitis (NEC),and bronchopulmonary dysplasia (BPD).The results of ophthalmological examinations by RetcamⅢ were also recorded.Spearman correlation analysis was used to identify the variables most significantly associated with ROP.Results There were 98 infants of ROP in group Ⅱ (total 764,12.8％).There was a significant association of ROP with variables (P ＜0.05),including BW,GA,and NOB.There was a significant association of ROP with diseases (P ＜ 0.05),including NRDS,neonatal asphyxia,intracranial hemorrhage,neonatal anemia,neonatal sepsis,NEC,and BPD.However,there was no association of ROP with diseases (P ＞ 0.05),including PDA,neonatal hyperbilirubinemia,and congenital heart disease.Conclusions RetcamⅢ can be used to screen retina of infants.ROP is still the most common eye disease in preterm infants.The incidence of ROP was 12.83％ in Wenzhou.Variables,including BW,GA,NOB,NRDS,neonatal asphyxia,intracranial hemorrhage,neonatal anemia,neonatal sepsis,NEC,and BPD,were the most significant factors associated with ROP.
