CAJ | 학술논문

目的分析番禺区8000例妇女宫颈HPV检查结果,了解番禺区妇女宫颈HPV感染率、亚型分型、年龄结构及宫颈病变情况.方法对8000例受检者进行HPV-DNA检测、对感染病例进行宫颈TCT检查及阴道镜病理检查.结果 HPV感染为炎症和尖锐湿疣9例,年龄25 ～ 42岁,主要感染型:6、11.病变级别分组为CIN Ⅰ 4例,年龄26～34岁,主要感染型:18、31、33.CINⅡ、Ⅲ11例,年龄24 ～ 57岁,主要感染型:16、58、33、52、51.原位癌1例,年龄43岁,主要感染型:31、33.结论 HPV感染的发生率有年轻化趋势,20～30岁、30～40岁、40～50岁3个年龄段为妇女宫颈病变的发病高峰期;HPV感染亚型中,低危型为6、11,高危型为16、18、31、33、51、52、58,且33型为番禺区主要高危型;多重感染与宫颈癌病变有相当密切的关系.
목적 분석번우구8000례부녀궁경HPV검사결과,료해번우구부녀궁경HPV감염솔、아형분형、년령결구급궁경병변정황.방법 대8000례수검자진행HPV-DNA검측、대감염병례진행궁경TCT검사급음도경병리검사.결과 HPV감염위염증화첨예습우9례,년령25 ～ 42세,주요감염형:6、11.병변급별분조위CIN Ⅰ 4례,년령26～34세,주요감염형:18、31、33.CINⅡ、Ⅲ11례,년령24 ～ 57세,주요감염형:16、58、33、52、51.원위암1례,년령43세,주요감염형:31、33.결론 HPV감염적발생솔유년경화추세,20～30세、30～40세、40～50세3개년령단위부녀궁경병변적발병고봉기;HPV감염아형중,저위형위6、11,고위형위16、18、31、33、51、52、58,차33형위번우구주요고위형;다중감염여궁경암병변유상당밀절적관계.
Objective To analyze 8000 cases of the human papilloma virus (HPV) inspection results in Panyu district,for understanding conditions of women infected with HPV,subtypes,age structure and cervical lesions.Method 8000 subjects were inspected by HPV-DNA testing,TCT examination and colposcopy pathology examination.Results HPV infection inflammation and 9 cases of condyloma acuminatum,aged 25-42,primary infection type:6,11,13.Lesion level subgroup CIN Ⅰ in 4 cases,aged 26-34,primary infection type:18,31,33.CIN Ⅱ-CIN Ⅲ in 11 cases,aged 24-57,primary infection type:16,58,33,52,51.Carcinoma in situ in 1 case (4％),aged 43,primary infection type:31,33.Conclusion HPV infection rate has the young tendency,in the 20-30 years,30-40 years,40-50 years as 3 age groups for women with cervical lesions of the peak incidence of infection; HPV subtype,low-risk types 6,11,high risk typel6,18,31,33,51,52,58,and the type 33 is the main high risk; multiplicity of infection and cervical cancer has a very close relationship.