国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2013年
12期
1733-1735
,共3页
曾淑云%邓文彬%邱宇%曾洪杰
曾淑雲%鄧文彬%邱宇%曾洪傑
증숙운%산문빈%구우%증홍걸
尿酸%肌酐%尿素氮%尿微量白蛋白
尿痠%肌酐%尿素氮%尿微量白蛋白
뇨산%기항%뇨소담%뇨미량백단백
Uric acid%Creatinine%Urea nitrogen%Urinary microalbumin
目的 探讨血尿酸与尿微量白蛋白及肾功能相关性.方法 回顾性分析本院2009年1月到2012年10月内科门诊就诊的185例血尿酸升高患者的血尿酸水平与尿微量白蛋白、血肌酐、血尿素氮之间的关系,进行统计学处理,并与血尿酸正常人群进行对照.结果 观察组尿微量白蛋白(73.51±54.87)mg/L、血肌酐(83.60±18.09)μmol/L、血尿素氮(5.31± 1.92) mmol/L均显著高于对照组的尿微量白蛋白(18.02±13.61) mg/L、血肌酐(67.84±15.84) μmol/L、血尿素氮(4.67±1.74) mmol/L,差异均有统计学意义(P＜0.05)；观察组尿微量白蛋白、血肌酐、血尿素氮均随病程延长而升高,差异均有统计学意义(P＜0.05)；血尿酸水平升高与尿微量白蛋白、血肌酐、血尿素氮水平正相关(P分别为0.005、0.034、0.042).结论 血尿酸升高可导致肾功能损害,早期干预有助于防治高尿酸致肾损害的进一步发展,减少尿毒症的发生.
目的 探討血尿痠與尿微量白蛋白及腎功能相關性.方法 迴顧性分析本院2009年1月到2012年10月內科門診就診的185例血尿痠升高患者的血尿痠水平與尿微量白蛋白、血肌酐、血尿素氮之間的關繫,進行統計學處理,併與血尿痠正常人群進行對照.結果 觀察組尿微量白蛋白(73.51±54.87)mg/L、血肌酐(83.60±18.09)μmol/L、血尿素氮(5.31± 1.92) mmol/L均顯著高于對照組的尿微量白蛋白(18.02±13.61) mg/L、血肌酐(67.84±15.84) μmol/L、血尿素氮(4.67±1.74) mmol/L,差異均有統計學意義(P＜0.05)；觀察組尿微量白蛋白、血肌酐、血尿素氮均隨病程延長而升高,差異均有統計學意義(P＜0.05)；血尿痠水平升高與尿微量白蛋白、血肌酐、血尿素氮水平正相關(P分彆為0.005、0.034、0.042).結論 血尿痠升高可導緻腎功能損害,早期榦預有助于防治高尿痠緻腎損害的進一步髮展,減少尿毒癥的髮生.
목적 탐토혈뇨산여뇨미량백단백급신공능상관성.방법 회고성분석본원2009년1월도2012년10월내과문진취진적185례혈뇨산승고환자적혈뇨산수평여뇨미량백단백、혈기항、혈뇨소담지간적관계,진행통계학처리,병여혈뇨산정상인군진행대조.결과 관찰조뇨미량백단백(73.51±54.87)mg/L、혈기항(83.60±18.09)μmol/L、혈뇨소담(5.31± 1.92) mmol/L균현저고우대조조적뇨미량백단백(18.02±13.61) mg/L、혈기항(67.84±15.84) μmol/L、혈뇨소담(4.67±1.74) mmol/L,차이균유통계학의의(P＜0.05)；관찰조뇨미량백단백、혈기항、혈뇨소담균수병정연장이승고,차이균유통계학의의(P＜0.05)；혈뇨산수평승고여뇨미량백단백、혈기항、혈뇨소담수평정상관(P분별위0.005、0.034、0.042).결론 혈뇨산승고가도치신공능손해,조기간예유조우방치고뇨산치신손해적진일보발전,감소뇨독증적발생.
Objective To discuss the relationship among serum uric acid,urinary microalbumin and renal function.Methods 185 medical clinic patients from January 2009 to October 2012 with higher serum uric acid level were studied.Retrospectively analysis was conducted to observe the relationship between their respective serum uric acid and urinary microalbumin,serum creatinine and blood urea nitrogen,statistical analysis,and compare with normal uric acid group.Results The urinary microalbumin,serum creatinine and blood urea nitrogen of observation group were significantly higher than those of control group (P＜0.05),and significantly elevated as extension of the course (P＜0.05).The elevation of serum uric acid level was positively related with the level of urinary microalbumin,serum creatinine and blood urea nitrogen.Conclusion Elevated serum uric acid can cause renal impairment.Early intervention would help to prevent from further development of renal damage caused by high uric acid and reduce the incidence of uremia.
