国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2013年
13期
1933-1936
,共4页
张晖%刘旭明%李康%杨燕君%刘妥英
張暉%劉旭明%李康%楊燕君%劉妥英
장휘%류욱명%리강%양연군%류타영
老年%上消化道出血%现状%影响因素
老年%上消化道齣血%現狀%影響因素
노년%상소화도출혈%현상%영향인소
Elderly%Hemorrhage in upper digestive tract%Status%Influencing factors
目的 了解老年上消化道溃疡(PU)出血的现状,探讨其可能影响因素,为临床治疗和开展有效干预提供依据.方法 采用回顾性分析方法,选取2008年1月至2012年12月在广州市番禺区何贤纪念医院确诊的PU患者共331例为研究对象,按年龄分为老年组(≥60岁)114例和非老年组(<60岁)217例,对两组患者的发病原因和并存疾病进行比较分析.结果 老年组(占50.88%)两种以上基础疾病患病率高于非老年组(占16.13%),差异有统计学意义(P<0.01).精神紧张或劳累过渡、吸烟史和饮酒史的发生率非老年组均高于老年组,差异有统计学意义(P<0.01).非老年组(占44.74%)幽门螺杆菌(HP)感染率高于老年组(占61.75%),差异有统计学意义(P<0.01).老年组服用降压药、抗凝药、非甾体抗炎药(NSAIDs)及合用多种药物者的比例均高于非老年组,差异均有统计学意义(P<0.01).结论 积极治疗基础疾病,合理使用降压药、抗凝药及NSAIDs药物对防治老年PU出血有重要意义.
目的 瞭解老年上消化道潰瘍(PU)齣血的現狀,探討其可能影響因素,為臨床治療和開展有效榦預提供依據.方法 採用迴顧性分析方法,選取2008年1月至2012年12月在廣州市番禺區何賢紀唸醫院確診的PU患者共331例為研究對象,按年齡分為老年組(≥60歲)114例和非老年組(<60歲)217例,對兩組患者的髮病原因和併存疾病進行比較分析.結果 老年組(佔50.88%)兩種以上基礎疾病患病率高于非老年組(佔16.13%),差異有統計學意義(P<0.01).精神緊張或勞纍過渡、吸煙史和飲酒史的髮生率非老年組均高于老年組,差異有統計學意義(P<0.01).非老年組(佔44.74%)幽門螺桿菌(HP)感染率高于老年組(佔61.75%),差異有統計學意義(P<0.01).老年組服用降壓藥、抗凝藥、非甾體抗炎藥(NSAIDs)及閤用多種藥物者的比例均高于非老年組,差異均有統計學意義(P<0.01).結論 積極治療基礎疾病,閤理使用降壓藥、抗凝藥及NSAIDs藥物對防治老年PU齣血有重要意義.
목적 료해노년상소화도궤양(PU)출혈적현상,탐토기가능영향인소,위림상치료화개전유효간예제공의거.방법 채용회고성분석방법,선취2008년1월지2012년12월재엄주시번우구하현기념의원학진적PU환자공331례위연구대상,안년령분위노년조(≥60세)114례화비노년조(<60세)217례,대량조환자적발병원인화병존질병진행비교분석.결과 노년조(점50.88%)량충이상기출질병환병솔고우비노년조(점16.13%),차이유통계학의의(P<0.01).정신긴장혹로루과도、흡연사화음주사적발생솔비노년조균고우노년조,차이유통계학의의(P<0.01).비노년조(점44.74%)유문라간균(HP)감염솔고우노년조(점61.75%),차이유통계학의의(P<0.01).노년조복용강압약、항응약、비치체항염약(NSAIDs)급합용다충약물자적비례균고우비노년조,차이균유통계학의의(P<0.01).결론 적겁치료기출질병,합리사용강압약、항응약급NSAIDs약물대방치노년PU출혈유중요의의.
Objective To provide support for clinical treatment and effective prevention of ulcer hemorrhage in upper digestive tract by exploring the current status of this condition in elderly people and exploring the possible influencing factors.Methods The data on 331 patients who had been diagnosed in our hospital during the period of January 2008 to December 2012 were retrospectively analyzed.The patients were divided into elderly group (≥60 years,114 patients) and non-elderly group (< 60 years,217 patients) according to their ages.The etiologies and coexisting diseases were analyzed and then compared between the two groups.Results The rate of two or more coexisting diseases was higher in the elderly group than in the non-elderly group (50.88% vs.16.13%,P<0.01).The rates of mental stress or overstrain and history of smoking and alcohol drinking were higher in the non-elderly group than in the elderly group,with a significant statistical difference (P<0.01).The rate of Helicobacter pylori infection was higher in the non-elderly group than in the elderly group (44.74% vs.61.75%,P<0.01).The percentage of taking antihypertensive drugs,anticoagulant drugs,or non-steroidal anti-inflammatory drugs (NSAIDs) alone or combination therapy was higher in the elderly group than in the non-elderly group,with a significant statistical difference (P<0.01).Conclusions Active treatment of underlying diseases,rational uses of antihypertensive drugs,NSAIDs,and anticoagulant agents are of important significance in the prevention and treatment of ulcer hemorrhage in upper digestive tract.