国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2013年
20期
3148-3151
,共4页
妊娠%胆汁淤积症%分度管理%妊娠结局
妊娠%膽汁淤積癥%分度管理%妊娠結跼
임신%담즙어적증%분도관리%임신결국
Gestation%Intrahepatic cholestasis during pregnancy (ICP)%Dividing management%Pregnancy outcome
目的 探讨妊娠期肝内胆汁淤积症(ICP)患者分度管理后的妊娠结局.方法 将142例围生期ICP患者以既定生化指标值为限,取轻度患者104例,重度患者38例,分为A、B两组,A组(实验组):轻度(A1)52例,重度(A2) 19例；B组(对照组):轻度(B1)52例,重度(B2)19例.A组按分度诊断、处理:A1组患者在孕41周之前,期待自然临产、阴道试产.A2组患者提前干预,计划剖宫产术终止妊娠.B组则不采用分度处理,全执行门诊或住院后的个性化治疗.观察两组的妊娠结局.结果 A、B两组ICP患者中,A组低体重儿11.3％、羊水粪染率11.3％、新生儿窒息率5.6％、剖宫产率32.4％、产后出血率5.6％.B组低体重儿19.7％、羊水粪染率15.5％、新生儿窒息率15.5％、剖宫产率64.8％、产后出血率9.9％.A、B两组比较差异有统计学意义(P＜0.05).结论 对ICP患者进行分度诊断和相应的合理处理,可以改善妊娠结局.
目的 探討妊娠期肝內膽汁淤積癥(ICP)患者分度管理後的妊娠結跼.方法 將142例圍生期ICP患者以既定生化指標值為限,取輕度患者104例,重度患者38例,分為A、B兩組,A組(實驗組):輕度(A1)52例,重度(A2) 19例；B組(對照組):輕度(B1)52例,重度(B2)19例.A組按分度診斷、處理:A1組患者在孕41週之前,期待自然臨產、陰道試產.A2組患者提前榦預,計劃剖宮產術終止妊娠.B組則不採用分度處理,全執行門診或住院後的箇性化治療.觀察兩組的妊娠結跼.結果 A、B兩組ICP患者中,A組低體重兒11.3％、羊水糞染率11.3％、新生兒窒息率5.6％、剖宮產率32.4％、產後齣血率5.6％.B組低體重兒19.7％、羊水糞染率15.5％、新生兒窒息率15.5％、剖宮產率64.8％、產後齣血率9.9％.A、B兩組比較差異有統計學意義(P＜0.05).結論 對ICP患者進行分度診斷和相應的閤理處理,可以改善妊娠結跼.
목적 탐토임신기간내담즙어적증(ICP)환자분도관리후적임신결국.방법 장142례위생기ICP환자이기정생화지표치위한,취경도환자104례,중도환자38례,분위A、B량조,A조(실험조):경도(A1)52례,중도(A2) 19례；B조(대조조):경도(B1)52례,중도(B2)19례.A조안분도진단、처리:A1조환자재잉41주지전,기대자연임산、음도시산.A2조환자제전간예,계화부궁산술종지임신.B조칙불채용분도처리,전집행문진혹주원후적개성화치료.관찰량조적임신결국.결과 A、B량조ICP환자중,A조저체중인11.3％、양수분염솔11.3％、신생인질식솔5.6％、부궁산솔32.4％、산후출혈솔5.6％.B조저체중인19.7％、양수분염솔15.5％、신생인질식솔15.5％、부궁산솔64.8％、산후출혈솔9.9％.A、B량조비교차이유통계학의의(P＜0.05).결론 대ICP환자진행분도진단화상응적합리처리,가이개선임신결국.
Objective To probe the outcome of intrahepatic cholestasis during pregnancy (ICP) in patients with pregnancy after dividing management.Methods 142 patients with ICP in the perinatal period were limited to establish biochemical indexes.These patients were divided into two groups:group A with 104 mild patients (experimental group),group B with 38 severe patients (control group).The experimental group included 52 mild cases (A1) and 19 severe cases (A2).The grading diagnosis and treatment were used in group A.The patients in group A1 were expected to natural labor and vaginal trial production before 41 weeks gestation,and the patients in group A2 were treated with early intervention and planned cesarean section termination of pregnancy.The patients in Group B were treated without grading diagnosis and treatment.The personalized treatment was used in group B.The pregnancy outcome of these two groups was observed.Results Between these two groups,there were 11.3％ of low-birth weight infants,11.3％ of amniotic fluid turbidity,5.6％of neonatal asphyxia,32.4％ of cesarean delivery and 5.6％ of postpartum hemorrhage in group A; while there were 19.7％ of low birth weight infants,15.5％ of amniotic fluid turbidity,15.5％ of neonatal asphyxia,64.8％of cesarean delivery and 9.9％ of postpartum hemorrhage in group B,showing more statistical significant difference (P＜0.05).Conclusion Grading diagnosis and corresponding proper treatment to patients with ICP can improve the pregnancy outcome.
