国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2013年
24期
3693-3696
,共4页
杨燕华%刘自爱%黄庆宁%黄虔
楊燕華%劉自愛%黃慶寧%黃虔
양연화%류자애%황경저%황건
2型糖尿病%左室舒张功能不全%心率变异性%B型尿钠肽
2型糖尿病%左室舒張功能不全%心率變異性%B型尿鈉肽
2형당뇨병%좌실서장공능불전%심솔변이성%B형뇨납태
Type 2 diabetes%Left ventricular diastolic dysfunction%Heart rate variability%Brain natriuretic peptide
目的 分析2型糖尿病伴左室舒张功能不全患者心率变异性与B型尿钠肽的关系.方法 收集100例B型尿钠肽≥100 pg/ml的2型糖尿病患者,研究其心率变异性与B型尿钠肽的相关性.心率变异性指标包括:SDNN-Index、RMSSD、PNN50,数据以平均值±标准差(M±SD)表示,用SPSS软件进行Pearson相关分析.结果 100例2型糖尿病伴心脏舒张功能不全患者SDNN-Index为(46.41±17.74) ms,RMSSD为(37.18±19.07) ms,PNN50为(18.88±15.21)％,SDNN-Index、RMSSD、PNN50与B型尿钠肽相关系数分别为-0.472、-0.434、-0.589,P均＜0.01.结论 2型糖尿病伴心脏舒张功能不全患者的心率变异性明显低于正常人,且与B型尿钠肽水平相关.
目的 分析2型糖尿病伴左室舒張功能不全患者心率變異性與B型尿鈉肽的關繫.方法 收集100例B型尿鈉肽≥100 pg/ml的2型糖尿病患者,研究其心率變異性與B型尿鈉肽的相關性.心率變異性指標包括:SDNN-Index、RMSSD、PNN50,數據以平均值±標準差(M±SD)錶示,用SPSS軟件進行Pearson相關分析.結果 100例2型糖尿病伴心髒舒張功能不全患者SDNN-Index為(46.41±17.74) ms,RMSSD為(37.18±19.07) ms,PNN50為(18.88±15.21)％,SDNN-Index、RMSSD、PNN50與B型尿鈉肽相關繫數分彆為-0.472、-0.434、-0.589,P均＜0.01.結論 2型糖尿病伴心髒舒張功能不全患者的心率變異性明顯低于正常人,且與B型尿鈉肽水平相關.
목적 분석2형당뇨병반좌실서장공능불전환자심솔변이성여B형뇨납태적관계.방법 수집100례B형뇨납태≥100 pg/ml적2형당뇨병환자,연구기심솔변이성여B형뇨납태적상관성.심솔변이성지표포괄:SDNN-Index、RMSSD、PNN50,수거이평균치±표준차(M±SD)표시,용SPSS연건진행Pearson상관분석.결과 100례2형당뇨병반심장서장공능불전환자SDNN-Index위(46.41±17.74) ms,RMSSD위(37.18±19.07) ms,PNN50위(18.88±15.21)％,SDNN-Index、RMSSD、PNN50여B형뇨납태상관계수분별위-0.472、-0.434、-0.589,P균＜0.01.결론 2형당뇨병반심장서장공능불전환자적심솔변이성명현저우정상인,차여B형뇨납태수평상관.
Objective To evaluate the correlation between he art rate variability and brain natriuretic peptide (BNP) in patients with type 2 diabetes and left ventricular diastolic dysfunction.Methods 100 patients with type 2 diabetes were included,all the patients' BNP level were over 100 pg/ml.SDNN-Index,RMSSD,PNN50 and BNP were measured,data were presented as (M ± SD).The correlation between heart rate variability and BNP level was assessed by Pearson Correlation Analysis (SPSS software).Results The correlation coefficient between SDNN-Index [(46.41 ± 17.74) ms] and BNP level was-0.472 (P ＜ 0.01);The correlation coefficient between RMSSD [(37.18 ± 19.07) ms] and BNP level was-0.434 (P ＜ 0.01); the correlation coefficient between PNN50[(18.88 ± 15.21)％] and BNP level was-0.589 (P ＜ 0.01).Conclusion The heart rate variability in patients with type 2 diabetes and left ventricular diastolic dysfunction is obviously lower than that of normal people,and significantly correlated with BNP level.
