国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2014年
2期
183-187
,共5页
H型高血压%冠心病%冠状动脉造影%低密度脂蛋白%同型半胱氨酸
H型高血壓%冠心病%冠狀動脈造影%低密度脂蛋白%同型半胱氨痠
H형고혈압%관심병%관상동맥조영%저밀도지단백%동형반광안산
H-hypertension%Coronary heart disease%Coronary angiography%Low density lipoprotein%Homocysteine
目的 探讨H型高血压、LDL对冠心病患者冠脉病变程度的影响.方法 选取我院2009年6月至2011年12月收治的158例冠心病患者为研究对象,根据有没有高血压分为高血压冠心病组和正常血压冠心病组,再按照血清同型半胱氨酸(Hcv)水平的不同,将高血压冠心病组分为H型高血压冠心病组(Hcy≥10μmol/L)和单纯性高血压冠心病组(Hcy＜10 μmol/L),根据冠状动脉造影结果分为单支病变、双支病变、多支病变三组,将冠状动脉造影正常者20例作为对照组,比较高血压冠心病组、正常血压冠心病组、H型高血压冠心病组和单纯性高血压冠心病组患者的Hcy、低密度脂蛋白(LDL)、冠状动脉狭窄程度及病变支数等指标,观察H型高血压对冠心病患者冠脉病变程度的影响.结果 H型高血压组血清Hcy、LDL水平、冠心病患者冠状动脉狭窄程度、病变支数明显高于单纯性高血压组、正常血压冠心病组和对照组(P＜0.01),具有统计学意义,而且狭窄程度越明显,病变支数越多,其血清Hcy、LDL水平越高.结论 H型高血压血清Hcy、LDL水平与冠心病患者冠状动脉狭窄程度及病变支数密切相关,监测血清Hcy、LDL水平变化对于冠心病及H型高血压患者早期诊断治疗具有非常重要意义.
目的 探討H型高血壓、LDL對冠心病患者冠脈病變程度的影響.方法 選取我院2009年6月至2011年12月收治的158例冠心病患者為研究對象,根據有沒有高血壓分為高血壓冠心病組和正常血壓冠心病組,再按照血清同型半胱氨痠(Hcv)水平的不同,將高血壓冠心病組分為H型高血壓冠心病組(Hcy≥10μmol/L)和單純性高血壓冠心病組(Hcy＜10 μmol/L),根據冠狀動脈造影結果分為單支病變、雙支病變、多支病變三組,將冠狀動脈造影正常者20例作為對照組,比較高血壓冠心病組、正常血壓冠心病組、H型高血壓冠心病組和單純性高血壓冠心病組患者的Hcy、低密度脂蛋白(LDL)、冠狀動脈狹窄程度及病變支數等指標,觀察H型高血壓對冠心病患者冠脈病變程度的影響.結果 H型高血壓組血清Hcy、LDL水平、冠心病患者冠狀動脈狹窄程度、病變支數明顯高于單純性高血壓組、正常血壓冠心病組和對照組(P＜0.01),具有統計學意義,而且狹窄程度越明顯,病變支數越多,其血清Hcy、LDL水平越高.結論 H型高血壓血清Hcy、LDL水平與冠心病患者冠狀動脈狹窄程度及病變支數密切相關,鑑測血清Hcy、LDL水平變化對于冠心病及H型高血壓患者早期診斷治療具有非常重要意義.
목적 탐토H형고혈압、LDL대관심병환자관맥병변정도적영향.방법 선취아원2009년6월지2011년12월수치적158례관심병환자위연구대상,근거유몰유고혈압분위고혈압관심병조화정상혈압관심병조,재안조혈청동형반광안산(Hcv)수평적불동,장고혈압관심병조분위H형고혈압관심병조(Hcy≥10μmol/L)화단순성고혈압관심병조(Hcy＜10 μmol/L),근거관상동맥조영결과분위단지병변、쌍지병변、다지병변삼조,장관상동맥조영정상자20례작위대조조,비교고혈압관심병조、정상혈압관심병조、H형고혈압관심병조화단순성고혈압관심병조환자적Hcy、저밀도지단백(LDL)、관상동맥협착정도급병변지수등지표,관찰H형고혈압대관심병환자관맥병변정도적영향.결과 H형고혈압조혈청Hcy、LDL수평、관심병환자관상동맥협착정도、병변지수명현고우단순성고혈압조、정상혈압관심병조화대조조(P＜0.01),구유통계학의의,이차협착정도월명현,병변지수월다,기혈청Hcy、LDL수평월고.결론 H형고혈압혈청Hcy、LDL수평여관심병환자관상동맥협착정도급병변지수밀절상관,감측혈청Hcy、LDL수평변화대우관심병급H형고혈압환자조기진단치료구유비상중요의의.
Objective To explore the influence of H-hypertension and LDL on the severity ot coronary artery in patients with coronary heart disease.Methods 158 patients with coronary heart disease admitted and treated in our hospital from June 2009 to December 2011 were selected.These patients were divided into a coronary artery disease with H-hypertension group and a coronary artery disease with normal blood pressure group according to whether the patients had hypertension.Then the former was divided into an H-hypertension group(Hcy ≥ 10 μ mol/L)and a simple hypertension group (Hcy＜10 μ mol/L) according to different levels of homocysteine (Hcy).Meanwhile,they were divided into a single branch abnormal coronary group,a two branches abnormal coronary group,and a three branches abnormal coronary group according to the angiography results.20 cases with normal angiography were taken as a control group.The levels of serum homocysteine and LDL,the severvity of coronary stenosis etc.in these groups were compared.The influence of H-hypertension and LDL on the severity of coronary arterv in patients with coronary heart disease was observed.Results The levels of serum homocysteine and LDL were higher,stenosis degree of coronary artery was more severe,and more coronary branches occurred stenosis in the H-hypertension group than in the simple hypertension group,normal blood pressure group,and control group,with statistical differences(P＜0.01).The levels of serum homocysteine and LDL increased with the severity of coronary artery and stenosis branch number.Conclusions The levels of serum homocysteine and LDL correlate with the severity of coronary artery and the stenosis branch number in the patients with coronary heart disease.The detection of thc levels of serum homocysteine and LDL has high clinical value in the early diagnosis and treatment of coronary heart disease and H-hypertension.
