国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2014年
2期
190-192
,共3页
硝苯地平控释片%氢氯噻嗪%老年高血压%降压
硝苯地平控釋片%氫氯噻嗪%老年高血壓%降壓
초분지평공석편%경록새진%노년고혈압%강압
Controlled release tablets of nifedipine%Hydrochlorothiazide%Senile hypertension%Antihypertension
目的 探讨盐酸贝那普利联合硝苯地平控释片或氢氯噻嗪治疗老年高血压的临床疗效比较.方法 选取140例3级老年高血压患者,随机分为观察组(70例)和对照组(70例),观察组给予贝那普利10 mg,早上1次,硝苯地平控释片30 mg,早上1次;对照组贝那普利10 mg,早上1次,氢氯噻嗪25 mg,早上1次,观察入选时和治疗4周后,收缩压和舒张压的变化.结果 治疗前,观察组平均血压为:(187.3±5.2)/(115.5±2.4) mmHg,对照组平均血压为:(186.2±5.5)/(116.2±2.2) mmHg,差异均无统计学意义(P＞0.05);治疗后,观察组平均血压为:(135.1±1.5)/(83.3±2.2) mmHg,对照组平均血压为:(142.2±2.1)/(89.1±2.5)mmHg,差异有统计学意义(P＜0.05);观察组的总有效率为90％,对照组的总有效率为80％,差异有统计学意义(P＜0.05).结论 观察组和对照组均能降低3级老年高血压,观察组疗效优于对照组,具有起效快、作用强、易于达标特点.
目的 探討鹽痠貝那普利聯閤硝苯地平控釋片或氫氯噻嗪治療老年高血壓的臨床療效比較.方法 選取140例3級老年高血壓患者,隨機分為觀察組(70例)和對照組(70例),觀察組給予貝那普利10 mg,早上1次,硝苯地平控釋片30 mg,早上1次;對照組貝那普利10 mg,早上1次,氫氯噻嗪25 mg,早上1次,觀察入選時和治療4週後,收縮壓和舒張壓的變化.結果 治療前,觀察組平均血壓為:(187.3±5.2)/(115.5±2.4) mmHg,對照組平均血壓為:(186.2±5.5)/(116.2±2.2) mmHg,差異均無統計學意義(P＞0.05);治療後,觀察組平均血壓為:(135.1±1.5)/(83.3±2.2) mmHg,對照組平均血壓為:(142.2±2.1)/(89.1±2.5)mmHg,差異有統計學意義(P＜0.05);觀察組的總有效率為90％,對照組的總有效率為80％,差異有統計學意義(P＜0.05).結論 觀察組和對照組均能降低3級老年高血壓,觀察組療效優于對照組,具有起效快、作用彊、易于達標特點.
목적 탐토염산패나보리연합초분지평공석편혹경록새진치료노년고혈압적림상료효비교.방법 선취140례3급노년고혈압환자,수궤분위관찰조(70례)화대조조(70례),관찰조급여패나보리10 mg,조상1차,초분지평공석편30 mg,조상1차;대조조패나보리10 mg,조상1차,경록새진25 mg,조상1차,관찰입선시화치료4주후,수축압화서장압적변화.결과 치료전,관찰조평균혈압위:(187.3±5.2)/(115.5±2.4) mmHg,대조조평균혈압위:(186.2±5.5)/(116.2±2.2) mmHg,차이균무통계학의의(P＞0.05);치료후,관찰조평균혈압위:(135.1±1.5)/(83.3±2.2) mmHg,대조조평균혈압위:(142.2±2.1)/(89.1±2.5)mmHg,차이유통계학의의(P＜0.05);관찰조적총유효솔위90％,대조조적총유효솔위80％,차이유통계학의의(P＜0.05).결론 관찰조화대조조균능강저3급노년고혈압,관찰조료효우우대조조,구유기효쾌、작용강、역우체표특점.
Objective To investigate the clinical efficacies of Benner Pury hydrochloride combined with nifedipine tablets or hydrochlorothiazide in the treatment of hypertension in the elderly.Methods 140patients with grade 3 hypertension were randomly divided into an observation group (70 cases) and a control group (70 cases).The observation group was given Benner Pury 10 mg one time and controlled release tablets of nifedipine 30 mg one time in the morning; the control group was given Benner Pury 10 mg one time and hydrochlorothiazide 25 mg one time in the morning.The changes of systolic and diastolic blood pressures were observed at the beginning of the selection and after 4 weeks' treatment.Results Before the treatment,the average blood pressure was (187.3 ± 5.2) / (115.5 ± 2.4) mmHg in the observation group and was (186.2 ± 5.5) / (116.2 ± 2.2) mmHg in the control group,with no statistical difference (P ＞ 0.05).After the treatment,the average blood pressure was (135.1 ± 1.5) / (83.3 ± 2.2) mmHg in the observation group and was (142.2 ± 2.1) / (89.1 ± 2.5) mmHg in the control group.The total effective rate was 90％ in the observation group and was 80％ in the control group,with a statistical difference (P＜0.05).Conclusions Grade 3 elderly hypertension decreased in both the observation group and the control group.The curative effect was better in the observation group than in the control group.The treatment method of the observation group had a rapid onset and strong action and was easy to meet the standard.
