CAJ | 학술논문

目的评价联合检测缺血修饰白蛋白(IMA)与心脏型脂肪酸结合蛋白(H-FABP)在急诊心源性胸痛(CCP)早期诊断中的临床意义.方法选取2013年1月至2014年1月我院收治的急诊胸痛＜3h的患者106例,检测IMA、H-FABP、心肌肌钙蛋白抗体(cTn1)、肌酸激酶同工酶(CK-MB)和心电图.结果最后97例确诊为心源性胸痛,其中,IMA或H-FABP阳性81例(83.5％),cTn1阳性62例(63.9％),CK-MB阳性52例(53.6％),心电图阳性43例(44.3％),IMA联合H-FABP检测与cTn1、CK-MB、心电图检测阳性率比较差异有统计学意义(P＜0.05).结论联合检测IMA与H-FABP在急诊心源性胸痛早期诊断中阳性检出率高,敏感度高,值得临床推广应用.
목적 평개연합검측결혈수식백단백(IMA)여심장형지방산결합단백(H-FABP)재급진심원성흉통(CCP)조기진단중적림상의의.방법 선취2013년1월지2014년1월아원수치적급진흉통＜3h적환자106례,검측IMA、H-FABP、심기기개단백항체(cTn1)、기산격매동공매(CK-MB)화심전도.결과 최후97례학진위심원성흉통,기중,IMA혹H-FABP양성81례(83.5％),cTn1양성62례(63.9％),CK-MB양성52례(53.6％),심전도양성43례(44.3％),IMA연합H-FABP검측여cTn1、CK-MB、심전도검측양성솔비교차이유통계학의의(P＜0.05).결론 연합검측IMA여H-FABP재급진심원성흉통조기진단중양성검출솔고,민감도고,치득림상추엄응용.
Objective To evaluate the clinical significance of the combined detection of ischemiamodified albumin (IMA) and heart-type fatty acid binding protein (H-FABP) in the early diagnosis of cardiac chest pain (CCP) at emergency room.Methods 106 patients diagnosed with chest pain less than 3 hours at the emergency room of our hospital from January,2013 to January,2014 were selcted as study objects,and then their IMA,H-FABP,cardiac troponin antibody (cTn1),and creatine kinase (CK-MB) were tested and they were checked with ECG.Results 97 patients were diagnosed with cardiac chest pain; among which,81 (83.5％) were positive in IMA or H-FABP,62 (63.9％) cTn1,52 (53.6％) CK-MB,and 43 (44.3％) ECG.There were statistical differences in test positive rate between IMA and H-FABP combined detection and cTn1,CK-MB,and ECG (P ＜ 0.05).Conclusions Combined detection of IMA and H-FABP in the early diagnosis of cardiac chest pain at emergency room has high detection rate and high sensitivity and deserves to be clinically generalized.