CAJ | 학술논문

目的探讨影响腮腺粘液表皮样癌患者预后的临床病理因素.方法对1986年至2010年在广州医科大学附属肿瘤医院住院治疗的61例原发于腮腺粘液表皮样癌进行回顾性队列研究.应用Kaplan-Meier法计算累计生存率,各因素间比较用Log-rank检验,多因素分析采用Cox回归分析模型.结果本组61例患者总的5年、10年生存率分别为81.2％、74.9％.多因素分析结果表明:切缘阳性的患者预后差(P＜0.05).结论手术治疗是腮腺粘液表皮样癌的首选治疗方法,切缘情况是影响硬腭鳞癌预后的独立因素.
목적 탐토영향시선점액표피양암환자예후적림상병리인소.방법 대1986년지2010년재엄주의과대학부속종류의원주원치료적61례원발우시선점액표피양암진행회고성대렬연구.응용Kaplan-Meier법계산루계생존솔,각인소간비교용Log-rank검험,다인소분석채용Cox회귀분석모형.결과 본조61례환자총적5년、10년생존솔분별위81.2％、74.9％.다인소분석결과표명:절연양성적환자예후차(P＜0.05).결론 수술치료시시선점액표피양암적수선치료방법,절연정황시영향경악린암예후적독립인소.
Objective To summarize the clinicopathologic prognostic factors of mucoepidermoid carcinoma of the parotid gland which is the most common malignant tumor of the salivary.Methods 61 cases of mucoepidermoid carcinoma of the parotid gland hospitalized in The Affiliated Tumor Hospital of Guangzhou Medical University,from 1986 to 2010 were reviewed retrospectively.The cumulative survival rate was analyzed by Kaplan-Meier method.And then the factors were compared using the Log-rank test.While the influencing factors were screened by Cox proportional hazards model.Results The 5-and 10-year overall survival rates were 81.2％ and 74.9％,respectively.Multivariate analysis showed that margin positive was independently associated with decrease survival rates (P ＜ 0.05).Conclusion Surgery therapy was the principal treatment method for mucoepidermoid carcinoma of the parotid gland.Margin is independent factor affecting the prognosis.