CAJ | 학술논문

目的研究北京市门头沟区病毒性腹泻病原学特点,为门头沟区病毒性腹泻疫情防控提供参考依据.方法 2011年4月-2013年3月选择门头沟区就诊人数较多的两家医院作为监测点,采用酶联免疫吸附法(enzyme linked immunosorbent assay,ELISA)检测轮状病毒,采用逆转录-聚合酶链反应(RT-PCR)方法检测杯状病毒.结果收集肠道门诊感染性腹泻患者251例,检测便标本251例,其中轮状病毒阳性率10.76％,杯状病毒阳性率为21.12％.轮状病毒和杯状病毒阳性率有显著差异(x2 =10.052,P=0.002).在年龄分布上,轮状病毒在60-69岁组阳性率最高,杯状病毒0-4岁组阳性率最高.在季节分布上,轮状病毒在12月份阳性率最高,杯状病毒在10月份阳性率最高.结论 2011-2013年门头沟区病毒性腹泻主要病原体是杯状病毒,轮状病毒也是重要病原体,病毒性腹泻人群中存在轮状病毒和杯状病毒的混合感染.
목적 연구북경시문두구구병독성복사병원학특점,위문두구구병독성복사역정방공제공삼고의거.방법 2011년4월-2013년3월선택문두구구취진인수교다적량가의원작위감측점,채용매련면역흡부법(enzyme linked immunosorbent assay,ELISA)검측륜상병독,채용역전록-취합매련반응(RT-PCR)방법검측배상병독.결과 수집장도문진감염성복사환자251례,검측편표본251례,기중륜상병독양성솔10.76％,배상병독양성솔위21.12％.륜상병독화배상병독양성솔유현저차이(x2 =10.052,P=0.002).재년령분포상,륜상병독재60-69세조양성솔최고,배상병독0-4세조양성솔최고.재계절분포상,륜상병독재12월빈양성솔최고,배상병독재10월빈양성솔최고.결론 2011-2013년문두구구병독성복사주요병원체시배상병독,륜상병독야시중요병원체,병독성복사인군중존재륜상병독화배상병독적혼합감염.
Objective To study the aetiology characteristics of virus diarrhea in Mentougou district of Beijing,to provide scientific basis for the prevention and control of viral diarrhea.Methods Two hospitals were selected as sentinel surveillance locations,the diarrhea cases were chosen as the surveillance subjects.Rotavirus were detected by ELISA.Human calicivirus were detected by RT-PCR.Results 251 cases were detected.10.76％ of the cases were rotavirus positive,21.12％ were calicivirus positive.There was significant difference between the infection rates of rotavirus and cabciwrus(x2=10.052,P =0.002).The mixed infection rate of rotavirus and calicivirus was 1.20％.The 60-69 age group showed the highest positive rate in rotavirus infection.0-4 age group had the highest positive rate in human calicivirus infection.The positive rate of rotavirus and human calicivirus peaked in December and October,respectively.Conclusions Human calicivirus is viral diarrhea predominant pathogens in Mentougou district of Beijing.Rota virus is also one of the important pathogens.There were patients concurrent infection with rotavirus and human calicivirus.