CAJ | 학술논문

目的调查乌鲁木齐地区住院患儿EB病毒(EB virus,EBV)感染的情况,为临床EBV感染诊断治疗提供参考.方法采用ELISA方法,对新疆维吾尔自治区人民医院儿科2011年5月至2012年5月1364例住院儿童进行EBV血清IgM、IgG抗体以及IgG抗体亲合力检测,并对EBV感染患儿的诊疗资料进行分析.结果住院儿童EBV感染率为89.7％ (1224/1364),近期感染率为15.5％ (221/1364).EBV感染患儿相关疾病诊断包括:支气管肺炎42.1％ (93/221)、肺炎25.3％(56/221)、贫血17.2％ (38/221)、肝炎综合征或黄疸14.5％ (32/221)、上呼吸道感染10.4％ (23/221)、化脓性扁桃体炎3.6％ (8/221)、传染性单核细胞增多症3.2％ (7/221)、病毒性脑炎3.2％ (7/221)、病毒性心肌炎2.7％ (6/221)、疱疹性咽峡炎1.4％ (3/221)以及其它6.3％(14/221).结论乌鲁木齐地区住院儿童EB病毒感染多见,临床表现多样,临床相关疾病多为呼吸道感染、肝炎综合症、贫血等.EBV血清IgM抗体以及IgG抗体亲合力检测是辅助诊断EB病毒感染的必要实验室手段.
목적 조사오로목제지구주원환인EB병독(EB virus,EBV)감염적정황,위림상EBV감염진단치료제공삼고.방법 채용ELISA방법,대신강유오이자치구인민의원인과2011년5월지2012년5월1364례주원인동진행EBV혈청IgM、IgG항체이급IgG항체친합력검측,병대EBV감염환인적진료자료진행분석.결과 주원인동EBV감염솔위89.7％ (1224/1364),근기감염솔위15.5％ (221/1364).EBV감염환인상관질병진단포괄:지기관폐염42.1％ (93/221)、폐염25.3％(56/221)、빈혈17.2％ (38/221)、간염종합정혹황달14.5％ (32/221)、상호흡도감염10.4％ (23/221)、화농성편도체염3.6％ (8/221)、전염성단핵세포증다증3.2％ (7/221)、병독성뇌염3.2％ (7/221)、병독성심기염2.7％ (6/221)、포진성인협염1.4％ (3/221)이급기타6.3％(14/221).결론 오로목제지구주원인동EB병독감염다견,림상표현다양,림상상관질병다위호흡도감염、간염종합증、빈혈등.EBV혈청IgM항체이급IgG항체친합력검측시보조진단EB병독감염적필요실험실수단.
Objective To understand clinical features and seropositive rate of children with EB virus in fection and provide basis for diagnosis and cure of EB virus.Methods The patients received medical treatment from MAY 2011 to May 2012 were recruited as subjects of this study.The IgM 、IgG and IgG antibody affinity were determined ELISA.The clinical feature,diagnosis,laboratory data of 1364 children infected with EB virus were analyzed retrospectively.Results Hospitalized children EBV infection rate was 89.7％ (1224/1364),the infection rate was 15.5 ％ (221/1364).The clinical manifestations of children infected by EB virus were diversity.The children were diagnosed as bronchial pneumonia(93,42.1％),pneumonia (56,25.3％),hypohemia (38,17.2％),hepatitis syndrome or jaundice (32,14.5％),upper respiratory tract infection (23,9.3％),viral encephalitis or myocarditis (13,5.2％),suppurative tonsillitis (8,3.2％),infectious mononucleosis (IM) (7,3.2％),herpangina (3,1.2％),others (14,6.3％).Conclusions Almost all systems of the body can be affected in EBV infected patients.The clinical manifestations were diversity,and related disease mainly with infectious mononucleosis (IM),pneumonia,bronchial pneumonia,bronchitis.