国际病毒学杂志
國際病毒學雜誌
국제병독학잡지
INTERNATIONAL JOURNAL OF VIROLOGY
2014年
3期
107-109
,共3页
王琦%李丹宇%周正月%刘晓丽
王琦%李丹宇%週正月%劉曉麗
왕기%리단우%주정월%류효려
人乳头瘤病毒%基因亚型%宫颈癌
人乳頭瘤病毒%基因亞型%宮頸癌
인유두류병독%기인아형%궁경암
Human papillomavirus%Ggenotype%Cervical cancer
目的 了解北京市朝阳区双桥医院妇科门诊不同年龄女性患者人乳头瘤病毒(human papilloma virus,HPV)亚型感染情况.方法 采用核酸分子快速导流杂交技术,对2009-2012年835例受检者宫颈分泌物进行HPV-DNA亚型检测.结果 538例女性患者中共检测到175例HPV阳性病例,其中高危亚型170例,低危亚型5例.高危亚型检出率居前5位依次为HPV-16 (31.4%)、52(20.0%)、58(17.1%)、56(14.3%)、66(14.3%).≥40岁以上年龄组HPV阳性率显著高于40岁以下年龄组.结论 高危型HPV-16、52、58、56、66亚型是北京市双桥医院人乳头瘤病毒感染的主要亚型,40岁以上人群是防治的重点.
目的 瞭解北京市朝暘區雙橋醫院婦科門診不同年齡女性患者人乳頭瘤病毒(human papilloma virus,HPV)亞型感染情況.方法 採用覈痠分子快速導流雜交技術,對2009-2012年835例受檢者宮頸分泌物進行HPV-DNA亞型檢測.結果 538例女性患者中共檢測到175例HPV暘性病例,其中高危亞型170例,低危亞型5例.高危亞型檢齣率居前5位依次為HPV-16 (31.4%)、52(20.0%)、58(17.1%)、56(14.3%)、66(14.3%).≥40歲以上年齡組HPV暘性率顯著高于40歲以下年齡組.結論 高危型HPV-16、52、58、56、66亞型是北京市雙橋醫院人乳頭瘤病毒感染的主要亞型,40歲以上人群是防治的重點.
목적 료해북경시조양구쌍교의원부과문진불동년령녀성환자인유두류병독(human papilloma virus,HPV)아형감염정황.방법 채용핵산분자쾌속도류잡교기술,대2009-2012년835례수검자궁경분비물진행HPV-DNA아형검측.결과 538례녀성환자중공검측도175례HPV양성병례,기중고위아형170례,저위아형5례.고위아형검출솔거전5위의차위HPV-16 (31.4%)、52(20.0%)、58(17.1%)、56(14.3%)、66(14.3%).≥40세이상년령조HPV양성솔현저고우40세이하년령조.결론 고위형HPV-16、52、58、56、66아형시북경시쌍교의원인유두류병독감염적주요아형,40세이상인군시방치적중점.
Objective To investigate the prevalence of human papilloma virus (HPV) among patients of the gynecology clinic in Beijing Shuangqiao hospital.Methods 835 specimens of cervical secretions were collected.The genotype of HPV was detected by flow-through hybridization.Results 175 cases were HPV-positive,among which 170 cases were high-risk subtypes,and only five cases of low-risk subtypes.The most common type was HPV16 (31.4%),followed by HPV-52 (20.0%),58 (17.1%),56(14.3%),and 66 (14.3%).The incidence of HPV infection among the group > 40 years old was obviously higher than others.Conclusions HPV16,52,58,56,and 66 were the most common types in the study population,and the prevention should focus on women > 40 years old.