CAJ | 학술논문

人类巨细胞病毒是一种嗜神经病毒,脑组织神经细胞是人类巨细胞病毒的敏感细胞.胎儿早期感染人类巨细胞病毒可导致脑坏死、钙化、脑发育迟缓,常见弥漫性脑损害,存活下来的胎儿以中枢神经系统受损最为突出,临床表现为小头畸形、脑瘫和癫(癎)及智力发育落后等,均以记忆障碍为主要症状.该文综述了人类巨细胞病毒宫内感染导致记忆障碍的研究进展.
인류거세포병독시일충기신경병독,뇌조직신경세포시인류거세포병독적민감세포.태인조기감염인류거세포병독가도치뇌배사、개화、뇌발육지완,상견미만성뇌손해,존활하래적태인이중추신경계통수손최위돌출,림상표현위소두기형、뇌탄화전(간)급지력발육락후등,균이기억장애위주요증상.해문종술료인류거세포병독궁내감염도치기억장애적연구진전.
Human cytomegalovirus(HCMV) is a neurotropic virus.Brain nerve cells are HCMV sensitive cell.Early fetal infection HCMV can lead to cerebral necrosis,calcification,cerebral developmental delay,common diffuse brain damage.The surviving fetus present prominent central nervous system damage,clinical manifestations of microcephaly,cerebral palsy and epilepsy and mental retardation,with memory impairment as the main symptoms.This paper reviews the HCMV intrauterine infection leads to memory impairment progress.