CAJ | 학술논문

目的探讨甲状腺乳头状癌(PTC)患者术后刺激状态甲状腺球蛋白(Tg)与颈部淋巴结转移的关系.方法 45例PTC患者行甲状腺全切或近全切并行颈部淋巴结清扫术,根据是否存在淋巴结转移分为L1和L02组,检测术后刺激状态Tg水平,采用统计学软件对数据进行t检验及相关性分析.结果 2组患者的年龄(t=-0.675,P＞0.05)、性别(x2=1.20,P＞0.05)差异无统计学意义,术后刺激状态Tg水平差异有统计学意义(t=4.167,P＜0.01).L1组术后刺激状态Tg水平与颈部淋巴结转移水平呈正相关(r=0.676,P＜0.01).结论 PTC患者术后刺激状态Tg水平与颈部淋巴结转移关系密切,是评价PTC术后131Ⅰ治疗疗效及判断预后的重要指标.
목적 탐토갑상선유두상암(PTC)환자술후자격상태갑상선구단백(Tg)여경부림파결전이적관계.방법 45례PTC환자행갑상선전절혹근전절병행경부림파결청소술,근거시부존재림파결전이분위L1화L02조,검측술후자격상태Tg수평,채용통계학연건대수거진행t검험급상관성분석.결과 2조환자적년령(t=-0.675,P＞0.05)、성별(x2=1.20,P＞0.05)차이무통계학의의,술후자격상태Tg수평차이유통계학의의(t=4.167,P＜0.01).L1조술후자격상태Tg수평여경부림파결전이수평정정상관(r=0.676,P＜0.01).결론 PTC환자술후자격상태Tg수평여경부림파결전이관계밀절,시평개PTC술후131Ⅰ치료료효급판단예후적중요지표.
Objective To discuss the correlation between the stimulated thyroglobulin (Tg) level after surgery in papillary thyroid carcinoma (PTC) and cervical lymph node metastasis.Methods Total thyroidectomy or subtotal thyroidectomy and radical cervical lymphadenectomy have been performed in 45 cases with PTC.All patients have been divided into two groups (L1 group and L0 group) according to whether lymph node metastasis exists.The stimulated Tg level after surgery were mesured and analyzed by t test with statistical software.Results There was no significant difference between the two groups in age (t=-0.675,P＞0.05) and gender(x2=1.20,P＞0.05),but significant difference could be found in stimulated Tg level after surgery between the two groups (t=4.167,P＜0.01).There was positive correlation between the stimulatied Tg level after surgery and cervical lymph node metastasis in L1 group(r=0.676,P＜0.01).Conclusion The stimulated Tg level after surgery is closely correlated to cervical lymph node metastasis in patients with PTC,which can be used as an assessment of the effect of the postsurgical 131Ⅰ therapy and prognosis.