国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2013年
5期
362-365
,共4页
支气管哮喘%气道重塑%气道平滑肌
支氣管哮喘%氣道重塑%氣道平滑肌
지기관효천%기도중소%기도평활기
Bronchial asthma%Airway remodeling%Airway smooth muscle
支气管哮喘(简称哮喘)是气道慢性炎症和组织改变共同参与的疾病.慢性炎症反应与气道重塑密切相关,炎症细胞和组织细胞释放多种细胞因子、趋化因子和生长因子,在气道组织里形成了复杂的信号环境促成了气道重塑.气道重塑包括一系列病理生理学特征.本文结合近年来哮喘气道重塑的文献,就病理学特点和最新机制性研究作一综述.
支氣管哮喘(簡稱哮喘)是氣道慢性炎癥和組織改變共同參與的疾病.慢性炎癥反應與氣道重塑密切相關,炎癥細胞和組織細胞釋放多種細胞因子、趨化因子和生長因子,在氣道組織裏形成瞭複雜的信號環境促成瞭氣道重塑.氣道重塑包括一繫列病理生理學特徵.本文結閤近年來哮喘氣道重塑的文獻,就病理學特點和最新機製性研究作一綜述.
지기관효천(간칭효천)시기도만성염증화조직개변공동삼여적질병.만성염증반응여기도중소밀절상관,염증세포화조직세포석방다충세포인자、추화인자화생장인자,재기도조직리형성료복잡적신호배경촉성료기도중소.기도중소포괄일계렬병리생이학특정.본문결합근년래효천기도중소적문헌,취병이학특점화최신궤제성연구작일종술.
Bronchial asthma (asthma) is a lung disease invloved by both airway chronic inflammatory and structural alterations.Remodeling is associated with airway chronic inflammatory response.Multiple cytokines,chemokines,and growth factors released from both inflammatory and structural cells in the airway tissue form a complex signaling environment that facilitate these structural changes,which contain a wide array of pathophysiologic features.In this paper,we will make a review on pathology feathers and latest mechanism researches based on recent literatures on airway remodeling in asthma.