国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2013年
12期
911-914
,共4页
陶梅梅%王洪武%周云芝%何晓蕴%梁素娟%李晶
陶梅梅%王洪武%週雲芝%何曉蘊%樑素娟%李晶
도매매%왕홍무%주운지%하효온%량소연%리정
气管腺样囊性癌%支气管镜%介入治疗%125Ⅰ粒子%并发症
氣管腺樣囊性癌%支氣管鏡%介入治療%125Ⅰ粒子%併髮癥
기관선양낭성암%지기관경%개입치료%125Ⅰ입자%병발증
Trachea adenoid cystic carcinoma%Bronchoscope%Interventional therapy%125Ⅰ radioactive seed%Complication
目的 评价支气管镜下不同方式治疗气管腺样囊性癌(TACC)的临床疗效和并发症.方法 回顾性分析煤炭总医院呼吸科自2008年1月至2012年10月收治的TACC患者共25例,比较不同支气管镜下治疗方法在治疗前后的气管直径、气促指数,并观察治疗后的并发症.结果 所有患者经治疗后症状均改善,气管直径由术前的(5.6±1.6)mm升高至(13.2±1.5)mm,气促评分由术前的2.8±0.8降至1.7±0.5(P＜0.01).术后各组患者均存在轻度咳嗽、咯血、咽痛,可自行缓解；支架置入组及125Ⅰ粒子植入组部分患者出现胸痛,可自行缓解.远期并发症主要为肿瘤复发导致的气管再狭窄,术后定期行气管镜检查随访,术后1个月、3个月氩等离子体凝切术(APC)+ CO2冷冻+125Ⅰ粒子植入组的再狭窄例数低于其他组.结论 支气管镜下不同治疗方式均可以改善TACC患者的症状,不同治疗方式的近期疗效无统计学差异,APC+ CO2冷冻+125Ⅰ粒子植入组患者再狭窄的几率可能更低.
目的 評價支氣管鏡下不同方式治療氣管腺樣囊性癌(TACC)的臨床療效和併髮癥.方法 迴顧性分析煤炭總醫院呼吸科自2008年1月至2012年10月收治的TACC患者共25例,比較不同支氣管鏡下治療方法在治療前後的氣管直徑、氣促指數,併觀察治療後的併髮癥.結果 所有患者經治療後癥狀均改善,氣管直徑由術前的(5.6±1.6)mm升高至(13.2±1.5)mm,氣促評分由術前的2.8±0.8降至1.7±0.5(P＜0.01).術後各組患者均存在輕度咳嗽、咯血、嚥痛,可自行緩解；支架置入組及125Ⅰ粒子植入組部分患者齣現胸痛,可自行緩解.遠期併髮癥主要為腫瘤複髮導緻的氣管再狹窄,術後定期行氣管鏡檢查隨訪,術後1箇月、3箇月氬等離子體凝切術(APC)+ CO2冷凍+125Ⅰ粒子植入組的再狹窄例數低于其他組.結論 支氣管鏡下不同治療方式均可以改善TACC患者的癥狀,不同治療方式的近期療效無統計學差異,APC+ CO2冷凍+125Ⅰ粒子植入組患者再狹窄的幾率可能更低.
목적 평개지기관경하불동방식치료기관선양낭성암(TACC)적림상료효화병발증.방법 회고성분석매탄총의원호흡과자2008년1월지2012년10월수치적TACC환자공25례,비교불동지기관경하치료방법재치료전후적기관직경、기촉지수,병관찰치료후적병발증.결과 소유환자경치료후증상균개선,기관직경유술전적(5.6±1.6)mm승고지(13.2±1.5)mm,기촉평분유술전적2.8±0.8강지1.7±0.5(P＜0.01).술후각조환자균존재경도해수、각혈、인통,가자행완해；지가치입조급125Ⅰ입자식입조부분환자출현흉통,가자행완해.원기병발증주요위종류복발도치적기관재협착,술후정기행기관경검사수방,술후1개월、3개월아등리자체응절술(APC)+ CO2냉동+125Ⅰ입자식입조적재협착례수저우기타조.결론 지기관경하불동치료방식균가이개선TACC환자적증상,불동치료방식적근기료효무통계학차이,APC+ CO2냉동+125Ⅰ입자식입조환자재협착적궤솔가능경저.
Objective To evaluate clinical curative effect and complications of different interventional methods by bronchoscopy on trachea adenoid cystic carcinoma (TACC).Methods The data of 25 patients with TACC in Meitan general hospital from January 2008 to October 2012 were retrospectively analyzed.The trachea diameter and dyspnea index were compared before and after treatment.Results The symptoms of all patients were improved after treatment.The trachea diameter increased significantly from (5.6± 1.6) mm to (13.2± 1.5) mm (P ＜0.01),and the dyspnea index decreased dramatically from 2.8±0.8 to 1.7±0.5 (P ＜0.01).Cough,haemoptysis,pharynx pain were the general complications following treatments.Trachea restenosis due to tumor relapse was major longterm complication.The incidence of trachea restenosis in 125Ⅰ radioactive seed implantation group was lower compared with the other groups during one month and three months follow-up.Conclusions The signs and symptoms were improved with different interventional methods by bronchoscopy in patients with TACC.The incidence of trachea restenosis may be low when patients receiving argon plasma coagulation,CO2 cryosurgery and 125Ⅰ radioactive seed implantation.
