CAJ | 학술논문

慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)是呼吸系统最常见的疾病之一,以气道、肺实质和肺血管的慢性炎症为特征,多种炎症细胞、细胞因子及炎性介质参与其发生发展.COPD发病率和致死率均较高,在未来数十年内其发病率仍将继续上升.因此,探索该病有效的治疗方法势在必行.本文就炎症反应与COPD肺功能分级关系作一综述,揭示炎症反应对COPD患者肺功能的影响.
만성조새성폐질병(chronic obstructive pulmonary disease,COPD)시호흡계통최상견적질병지일,이기도、폐실질화폐혈관적만성염증위특정,다충염증세포、세포인자급염성개질삼여기발생발전.COPD발병솔화치사솔균교고,재미래수십년내기발병솔잉장계속상승.인차,탐색해병유효적치료방법세재필행.본문취염증반응여COPD폐공능분급관계작일종술,게시염증반응대COPD환자폐공능적영향.
Chronic obstructive pulmonary disease (COPD) is one of the most common respiratory diseases in the world.COPD is characterized by chronic inflammation in airways,lung parenchyma,and pulmonary vessels.A variety of inflammatory cells,cytokines,and inflammatory mediators participate in the development of COPD.Its morbidity and mortality will continue rising in the coming decades.Therefore,it is imperative to explore new effective therapeutic methods for this disease.This article reviews the association of inflammation and lung function to understand the influence of inflammation on pulmonary function in COPD.