CAJ | 학술논문

目的探讨无创机械通气救治伴有意识障碍慢性阻塞性肺疾病急性加重期(AECOPD)呼吸衰竭患者成功的相关因素.方法 AECOPD伴有意识障碍的重症呼吸衰竭患者54例,接受BiPAP呼吸机治疗.按照治疗效果分为成功组和失败组,比较两组患者各项指标及变化,进行Logistic回归分析,寻找无创通气成功的相关因素.结果 NIPPV失败组患者稳定期FEV1％pred较高,PaCO2值较低,治疗后GCS评分较低,pH值较低,PaCO2较高,均较NIPPV成功组明显.Logistic回归分析提示,治疗后GCS评分NIPPV后期失败有显著影响.结论治疗后GCS评分是NIPPV治疗伴有意识障碍AECOPD呼吸衰竭患者成功的相关因素.
목적 탐토무창궤계통기구치반유의식장애만성조새성폐질병급성가중기(AECOPD)호흡쇠갈환자성공적상관인소.방법 AECOPD반유의식장애적중증호흡쇠갈환자54례,접수BiPAP호흡궤치료.안조치료효과분위성공조화실패조,비교량조환자각항지표급변화,진행Logistic회귀분석,심조무창통기성공적상관인소.결과 NIPPV실패조환자은정기FEV1％pred교고,PaCO2치교저,치료후GCS평분교저,pH치교저,PaCO2교고,균교NIPPV성공조명현.Logistic회귀분석제시,치료후GCS평분NIPPV후기실패유현저영향.결론 치료후GCS평분시NIPPV치료반유의식장애AECOPD호흡쇠갈환자성공적상관인소.
Objective To investigate the factors related to the success of noninvasive ventilation in the treatment of conscious disturbance due to acute exacerbation of chronic obstructive pulmonary disease (AECOPD) complicated with respiratory failure.Methods Fifty-four patients with conscious disturbance due to AECOPD complicated with respiratory failure were selected in the study,that treated by BiPAP ventilation.They were divided into effective group and failure group according to the curative effect,clinical and physiological parameters were analyzed comparatively between two groups,multi-variable logistic regression analysis was used to find the predictive factors of the success in noninvasive ventilation.Results In stable phase,FEV1 ％ predicted was higher,PaCO2 values was lower significantly in patients in NIPPV failure group who also had a lower GCS compared with NIPPV success group.Multi-variable logistic analysis suggests statistical significance in GCS after 2 h ventilation.Conclusions The failure of NIPPV in patients with conscious disturbance due to AECOPD complicated with respiratory failure was influenced by GCS after 2 h ventilation.