国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2013年
22期
1696-1699
,共4页
自荧光支气管镜%支气管镜%非小细胞肺癌%分期
自熒光支氣管鏡%支氣管鏡%非小細胞肺癌%分期
자형광지기관경%지기관경%비소세포폐암%분기
Autofluorescence bronchoscopy%Bronchoscopy%Non-small cell lung cancer%Staging
目的 探讨自荧光支气管镜(AFB)在非小细胞肺癌(NSCLC)气管支气管腔受侵T分期的应用和临床价值.方法 回顾性分析60例行AFB检查的NSCLC.患者常规行白光支气管镜(WLB)和AFB检查.比较WLB与AFB检查对NSCLC气管支气管腔内肿瘤边缘的判定,根据肿瘤边界黏膜活检结果,确定气管支气管腔内肿瘤受侵T分期.结果 60例患者中WLB检查T分期情况:T1 25例,T220例,T3 9例,T4 6例.AFB检查T分期情况:T1 30例,T2 16例,T3 6例,T4 8例.病理检查T分期情况:T1 29例,T2 17例,T3 6例,T4 8例.WLB与病理检查对肺癌T分期比较:T2、T3、T4期差异有统计学意义(P＜0.05),T1期差异无统计学意义(P＞0.05).AFB与病理检查对肺癌T分期比较,差异均无统计学意义(P值均＞0.05).结论 AFB较WLB在NSCLC分期上有一定优势,准确性更高.但由于AFB特异性稍差,在个别患者存在假阳性,因此必须结合WLB检查综合判定结果.
目的 探討自熒光支氣管鏡(AFB)在非小細胞肺癌(NSCLC)氣管支氣管腔受侵T分期的應用和臨床價值.方法 迴顧性分析60例行AFB檢查的NSCLC.患者常規行白光支氣管鏡(WLB)和AFB檢查.比較WLB與AFB檢查對NSCLC氣管支氣管腔內腫瘤邊緣的判定,根據腫瘤邊界黏膜活檢結果,確定氣管支氣管腔內腫瘤受侵T分期.結果 60例患者中WLB檢查T分期情況:T1 25例,T220例,T3 9例,T4 6例.AFB檢查T分期情況:T1 30例,T2 16例,T3 6例,T4 8例.病理檢查T分期情況:T1 29例,T2 17例,T3 6例,T4 8例.WLB與病理檢查對肺癌T分期比較:T2、T3、T4期差異有統計學意義(P＜0.05),T1期差異無統計學意義(P＞0.05).AFB與病理檢查對肺癌T分期比較,差異均無統計學意義(P值均＞0.05).結論 AFB較WLB在NSCLC分期上有一定優勢,準確性更高.但由于AFB特異性稍差,在箇彆患者存在假暘性,因此必鬚結閤WLB檢查綜閤判定結果.
목적 탐토자형광지기관경(AFB)재비소세포폐암(NSCLC)기관지기관강수침T분기적응용화림상개치.방법 회고성분석60례행AFB검사적NSCLC.환자상규행백광지기관경(WLB)화AFB검사.비교WLB여AFB검사대NSCLC기관지기관강내종류변연적판정,근거종류변계점막활검결과,학정기관지기관강내종류수침T분기.결과 60례환자중WLB검사T분기정황:T1 25례,T220례,T3 9례,T4 6례.AFB검사T분기정황:T1 30례,T2 16례,T3 6례,T4 8례.병리검사T분기정황:T1 29례,T2 17례,T3 6례,T4 8례.WLB여병리검사대폐암T분기비교:T2、T3、T4기차이유통계학의의(P＜0.05),T1기차이무통계학의의(P＞0.05).AFB여병리검사대폐암T분기비교,차이균무통계학의의(P치균＞0.05).결론 AFB교WLB재NSCLC분기상유일정우세,준학성경고.단유우AFB특이성초차,재개별환자존재가양성,인차필수결합WLB검사종합판정결과.
Objective To investigate application and clinical value of autofluorescence bronchoscopy (AFB) in tracheobronchial invasion T staging in non small cell lung cancer.Methods 60 non-small cell lung cancer patients who had performed AFB were retrospectively analyzed.They all had performed white light bronchoscopy (WLB) and AFB examination.We compared WLB and AFB examination on non-small cell lung cancer tracheobronchial lumen edge determination.We determined the tracheobronchial intraluminal tumor invasion T stage according to the tumor boundary biopsy results.Results In 60 patients,Tstaging situations of WLB check:T1 (25 cases),T2 (20 cases),T3 (nine cases),T4 (six cases).T staging situations of AFB check:T1 (30 cases),T2 (16 cases),T3 (six cases),T4 (eight cases).T staging situations of pathology check:T1 (29 cases),T2 (17 cases),T3 (six cases),T4 (eight cases).There was statistical difference between WLB and pathology check in T2,T3,and T4 staging (P ＜0.05),and no statistical difference in T1 staging (P ＞ 0.05).There was no statistical difference between AFB and pathology check in T staging (P ＞ 0.05).Conclusions AFB has certain advantages and higher accuracy than WLB in clinical staging of non small cell lung cancer.However,AFB has lower specificity,we must therefore combine with WLB inspection to assess synthetically results because of false position in individual patients.
