CAJ | 학술논문

目的探讨肺功能检测在慢性阻塞性肺疾病(COPD)诊断中的意义.方法通过对60例COPD患者的肺功能进行检测,并与74例正常人进行对照,观察COPD患者肺功能的特点.结果 COPD轻度、中度、重度和极重度的比例分别为23.7％、42.4％、25.4％和8.5％,并且4组之间的百分比、男女比例、年龄差异均无统计学意义(P＞0.05).除COPD轻度与对照组的FEV1％ pred差异无统计学意义(P＞0.05)外,COPD轻度、中度、重度和极重度与对照组的FEV1％pred、FEV1/FVC、DLCO和DLCO/VA差异均有统计学意义(P＜0.05).COPD轻度、中度、重度和极重度4组FEV1％pred随COPD的严重程度逐渐降低,且组间比较差异有统计学意义(P＜0.05).COPD患者肺功能各指标FEV1、FEV1/FVC、DLCO、DLCO/VA间均有良好的相关性(P＜0.05).结论 COPD患者FEV1、FEV1/FVC、DLCO、DLCO/VA较正常健康人降低,其肺通气功能和肺弥散功能具有良好的相关性,提示肺功能检测在COPD诊断中具有非常重要的临床意义,应予积极推广.
목적 탐토폐공능검측재만성조새성폐질병(COPD)진단중적의의.방법 통과대60례COPD환자적폐공능진행검측,병여74례정상인진행대조,관찰COPD환자폐공능적특점.결과 COPD경도、중도、중도화겁중도적비례분별위23.7％、42.4％、25.4％화8.5％,병차4조지간적백분비、남녀비례、년령차이균무통계학의의(P＞0.05).제COPD경도여대조조적FEV1％ pred차이무통계학의의(P＞0.05)외,COPD경도、중도、중도화겁중도여대조조적FEV1％pred、FEV1/FVC、DLCO화DLCO/VA차이균유통계학의의(P＜0.05).COPD경도、중도、중도화겁중도4조FEV1％pred수COPD적엄중정도축점강저,차조간비교차이유통계학의의(P＜0.05).COPD환자폐공능각지표FEV1、FEV1/FVC、DLCO、DLCO/VA간균유량호적상관성(P＜0.05).결론 COPD환자FEV1、FEV1/FVC、DLCO、DLCO/VA교정상건강인강저,기폐통기공능화폐미산공능구유량호적상관성,제시폐공능검측재COPD진단중구유비상중요적림상의의,응여적겁추엄.
Objective To explore the significance of pulmonary function testing in the diagnosis of chronic obstructive pulmonary disease(COPD).Methods Sixty patients with COPD for lung function testing while 74 cases of normal controls to observe the characteristics of pulmonary function of patients with COPD.Results The proportion of mild,moderate,severe and very severe of COPD patients was 23.7％,42.4％,25.4％ and 8.5％,and the percentage difference among the four groups,male to female ratio differences,age differences were not statistically significant (P ＞ 0.05).The FEV1％ pred,FEV1/ FVC,DLCO and DLCO/VA of the mild,moderate,severe and very severe of COPD patients were significantly lower than the control group (P ＜0.05),except the FEV1 ％pred of mild of COPD (P ＞ 0.05).The FEV1％pred of mild,moderate,severe and very severe of COPD decreased with the severity of COPD,coparation between each two groups were statistically significant (P ＜0.05).There is a good correlation between each lung function index,such as FEV1,FEV1/FVC,DLCO and DLCO/VA of COPD patients(P ＜0.05).Conclusions The FEV1,FEV1/FVC,DLCO,DLCO/VA of patients with COPD were lower than normal healthy people,their pulmonary ventilation function and pulmonary diffusion function had a good correlation,suggesting that lung function testing in the diagnosis of COPD had a very important clinical significance,and should be actively promoted.