国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2013年
24期
1857-1860,封3
,共5页
继发性肺肿瘤%良性转移性平滑肌瘤%子宫平滑肌瘤
繼髮性肺腫瘤%良性轉移性平滑肌瘤%子宮平滑肌瘤
계발성폐종류%량성전이성평활기류%자궁평활기류
Secondary lung neoplasms%Benign metastasizing leiomyoma%Uterus leiomyoma
目的 分析肺良性转移性平滑肌瘤的临床特点,加强临床医师对其的认识.方法 对国内报道的总共39例肺良性转移性平滑肌瘤的资料进行整理、分析.结果 39例均为女性,平均年龄43.8岁;94.9％有子宫肌瘤手术病史,术后发现肺部转移病灶的时间平均8.3年;呼吸道症状不明显,主要为咳嗽,占28.2％;胸部影像学表现主要为双肺多发结节,占76.9％,其次为单发结节或肿块,占15.4％;病灶直径最大为7 cm,结节边界基本比较清晰,未见钙化及强化.雌激素受体阳性率为92.9％,孕激素受体阳性率为96.4％.结论 肺良性转移性平滑肌瘤多发生在有子宫平滑肌瘤病史的女性,症状不明显,影像学主要表现为双肺多发结节,大部分病例雌激素受体及孕激素受体表达阳性,手术切除及抗雌激素是主要的治疗方法.
目的 分析肺良性轉移性平滑肌瘤的臨床特點,加彊臨床醫師對其的認識.方法 對國內報道的總共39例肺良性轉移性平滑肌瘤的資料進行整理、分析.結果 39例均為女性,平均年齡43.8歲;94.9％有子宮肌瘤手術病史,術後髮現肺部轉移病竈的時間平均8.3年;呼吸道癥狀不明顯,主要為咳嗽,佔28.2％;胸部影像學錶現主要為雙肺多髮結節,佔76.9％,其次為單髮結節或腫塊,佔15.4％;病竈直徑最大為7 cm,結節邊界基本比較清晰,未見鈣化及彊化.雌激素受體暘性率為92.9％,孕激素受體暘性率為96.4％.結論 肺良性轉移性平滑肌瘤多髮生在有子宮平滑肌瘤病史的女性,癥狀不明顯,影像學主要錶現為雙肺多髮結節,大部分病例雌激素受體及孕激素受體錶達暘性,手術切除及抗雌激素是主要的治療方法.
목적 분석폐량성전이성평활기류적림상특점,가강림상의사대기적인식.방법 대국내보도적총공39례폐량성전이성평활기류적자료진행정리、분석.결과 39례균위녀성,평균년령43.8세;94.9％유자궁기류수술병사,술후발현폐부전이병조적시간평균8.3년;호흡도증상불명현,주요위해수,점28.2％;흉부영상학표현주요위쌍폐다발결절,점76.9％,기차위단발결절혹종괴,점15.4％;병조직경최대위7 cm,결절변계기본비교청석,미견개화급강화.자격소수체양성솔위92.9％,잉격소수체양성솔위96.4％.결론 폐량성전이성평활기류다발생재유자궁평활기류병사적녀성,증상불명현,영상학주요표현위쌍폐다발결절,대부분병례자격소수체급잉격소수체표체양성,수술절제급항자격소시주요적치료방법.
Objective To investigate the clinical features of pulmonary benign metastasizing leiomyoma and enhance the consciousness to it.Methods A total of 39 cases of pulmonary benign metastasizing leiomyoma were reported in china,and their data were analyzed.Results 39 cases were female,with mean age of 43.8 years old.94.9％ patients had uterine leiomyoma surgery and pulmonary metastasis were found after surgery with mean time of 8.3 years.Respiratory symptom was not obvious and cough was the main symptom (28.2％).Multiple pulmonary lesions were found (76.9％) on chest imaging,followed by single nodules or mass (15.4％).Lesions maximumal diameter was 7 cm.Most lesions were smoothly marginated with well-defined borders,without calcification and aggrandizement in CT.Positive rates of estrogen receptor and progestogen receptor were 92.9％ and 96.4 ％,respectively.Conclusions Pulmonary benign metastasizing leiomyoma usually occurs in women after uterine leiomyoma surgery,without obvious symptom.Multiple pulmonary lesions are found in chest imaging.The expressions of estrogen receptor and progesterone receptor are positive in most cases,and surgical resection and anti-estrogen are the effective treatment.
