国际医学寄生虫病杂志
國際醫學寄生蟲病雜誌
국제의학기생충병잡지
INTERNATIONAL JOURNAL OF MEDICAL PARASITIC DISEASES
2013年
2期
83-88
,共6页
高金彬%黄亚民%朱玉芳%贺泳%沈才祥%乔长安
高金彬%黃亞民%硃玉芳%賀泳%瀋纔祥%喬長安
고금빈%황아민%주옥방%하영%침재상%교장안
血吸虫病%空腹血糖%传播阻断
血吸蟲病%空腹血糖%傳播阻斷
혈흡충병%공복혈당%전파조단
Schistosomiasis%Fasting plasma glucose%Transmission interrupted
目的 评价血吸虫病传播阻断地区中老年人空腹血糖水平,分析其与血吸虫病等因素之间的关系.方法 选择高邮市毛港村有血吸虫病史且已治愈15年以上者100人,性别、年龄相近的无血吸虫病史300人,检测空腹的血糖水平,同时调查糖尿病史、胆囊病史以及HBsAg阳性等伴随疾病,分析有、无血吸虫病史人群在不同性别、年龄、职业、文化程度,以及伴随胆囊病、HBsAg阳性等之间的血糖水平.结果 该村人群平均血糖水平为(5.57±1.59) mmol/L,95％CI为(5.41～5.72) mmol/L,空腹血糖受损(impaired fasting glucose,IFG)、空腹高血糖(diabetes mellitus,DM)的发生率均为6.75％.有血吸虫病史人群血糖水平为(5.60±1.78) mmol/L,95％CI为(5.29～6.01) mmol/L;无血吸虫病史人群血糖水平为(5.56±1.52) mmol/L,95％CI为(5.37～5.74) mmol/L;二者在不同性别、年龄、职业、文化程度,以及伴随胆囊病、HBsAg阳性等之间的血糖水平差异无统计学意义,除工人间的DM差异有统计学意义(x2=5.50,P＜0.05)外,其余各组间的IFG、DM发生率差异无统计学意义.除职业组农民外,其他组别间有血吸虫病史人群DM的发生率均大于无病史人群,其中男性组、40～59岁组、工人组、初中以上文化程度组有血吸虫病史者人群DM的发生率约为无病史者的8、2、12、8倍.在多数组别中有血吸虫病史人群血糖95％CI一般高于无病史人群,唯有血吸虫病史组中95％CI上限达到IFG的水平,其中女性性别组、60～69岁年龄组、工人职业组、文盲和初中以上文化程度组的95％CI上限分别为6.43、6.80、6.50、6.35、6.80 mmol/L,其余各组95％CI上限在正常值以内.结论 血吸虫病患者及时治愈后,其血糖水平与正常人群无明显差别,但部分中老年患者糖耐量受损的风险可能会增加.
目的 評價血吸蟲病傳播阻斷地區中老年人空腹血糖水平,分析其與血吸蟲病等因素之間的關繫.方法 選擇高郵市毛港村有血吸蟲病史且已治愈15年以上者100人,性彆、年齡相近的無血吸蟲病史300人,檢測空腹的血糖水平,同時調查糖尿病史、膽囊病史以及HBsAg暘性等伴隨疾病,分析有、無血吸蟲病史人群在不同性彆、年齡、職業、文化程度,以及伴隨膽囊病、HBsAg暘性等之間的血糖水平.結果 該村人群平均血糖水平為(5.57±1.59) mmol/L,95％CI為(5.41～5.72) mmol/L,空腹血糖受損(impaired fasting glucose,IFG)、空腹高血糖(diabetes mellitus,DM)的髮生率均為6.75％.有血吸蟲病史人群血糖水平為(5.60±1.78) mmol/L,95％CI為(5.29～6.01) mmol/L;無血吸蟲病史人群血糖水平為(5.56±1.52) mmol/L,95％CI為(5.37～5.74) mmol/L;二者在不同性彆、年齡、職業、文化程度,以及伴隨膽囊病、HBsAg暘性等之間的血糖水平差異無統計學意義,除工人間的DM差異有統計學意義(x2=5.50,P＜0.05)外,其餘各組間的IFG、DM髮生率差異無統計學意義.除職業組農民外,其他組彆間有血吸蟲病史人群DM的髮生率均大于無病史人群,其中男性組、40～59歲組、工人組、初中以上文化程度組有血吸蟲病史者人群DM的髮生率約為無病史者的8、2、12、8倍.在多數組彆中有血吸蟲病史人群血糖95％CI一般高于無病史人群,唯有血吸蟲病史組中95％CI上限達到IFG的水平,其中女性性彆組、60～69歲年齡組、工人職業組、文盲和初中以上文化程度組的95％CI上限分彆為6.43、6.80、6.50、6.35、6.80 mmol/L,其餘各組95％CI上限在正常值以內.結論 血吸蟲病患者及時治愈後,其血糖水平與正常人群無明顯差彆,但部分中老年患者糖耐量受損的風險可能會增加.
목적 평개혈흡충병전파조단지구중노년인공복혈당수평,분석기여혈흡충병등인소지간적관계.방법 선택고유시모항촌유혈흡충병사차이치유15년이상자100인,성별、년령상근적무혈흡충병사300인,검측공복적혈당수평,동시조사당뇨병사、담낭병사이급HBsAg양성등반수질병,분석유、무혈흡충병사인군재불동성별、년령、직업、문화정도,이급반수담낭병、HBsAg양성등지간적혈당수평.결과 해촌인군평균혈당수평위(5.57±1.59) mmol/L,95％CI위(5.41～5.72) mmol/L,공복혈당수손(impaired fasting glucose,IFG)、공복고혈당(diabetes mellitus,DM)적발생솔균위6.75％.유혈흡충병사인군혈당수평위(5.60±1.78) mmol/L,95％CI위(5.29～6.01) mmol/L;무혈흡충병사인군혈당수평위(5.56±1.52) mmol/L,95％CI위(5.37～5.74) mmol/L;이자재불동성별、년령、직업、문화정도,이급반수담낭병、HBsAg양성등지간적혈당수평차이무통계학의의,제공인간적DM차이유통계학의의(x2=5.50,P＜0.05)외,기여각조간적IFG、DM발생솔차이무통계학의의.제직업조농민외,기타조별간유혈흡충병사인군DM적발생솔균대우무병사인군,기중남성조、40～59세조、공인조、초중이상문화정도조유혈흡충병사자인군DM적발생솔약위무병사자적8、2、12、8배.재다수조별중유혈흡충병사인군혈당95％CI일반고우무병사인군,유유혈흡충병사조중95％CI상한체도IFG적수평,기중녀성성별조、60～69세년령조、공인직업조、문맹화초중이상문화정도조적95％CI상한분별위6.43、6.80、6.50、6.35、6.80 mmol/L,기여각조95％CI상한재정상치이내.결론 혈흡충병환자급시치유후,기혈당수평여정상인군무명현차별,단부분중노년환자당내량수손적풍험가능회증가.
Objective To investigate the fasting plasma glucose level in the middle aged and aged people in schistosomiasis transmission interrupted areas and analyze its relevance to schistosomiasis.Methods One hundred cured schistosomiasis patients and 300 residents at same age without shistosomiasis history in Maogang village,Gaoyou City were investigated.The fasting plasma glucose level was detected while the accompanied diseases such as diabetes,gallbladder infection and HBsAg etc.were investigated.The difference of the fasting plasma glucose level between with or without schistosomiasis history,with or without accompanied diseases and different gender,age,occupation and educational level was then analyzed.Results The average fasting plasma glucose of the population in the village was (5.57± 1.59) mmol/L,95％CI was (5.41-5.72) mmol/L.The incidence of impaired fasting glucose (IFG) as well as diabetes mellitus (DM) was 6.75％.The average fasting plasma glucose of the cured schistosomiasis patients was (5.60 ± 1.78) mmol/L,95％CI was (5.29-6.01) mmol/L,while that of the residents without shistosomiasis history was (5.56 ± 1.52) mmol/L,95％CI was (5.37-5.74)mmol/L,the difference between two groups was not statistically significant no matter what gender,age,occupation,educational level and accompanied diseases.There was no significant difference for IFG and DM among various groups except the incidence of DM between worker groups (x2=5.50,P＜0.05).The incidence of DM in cured schistosomiasis patients was higher than that in residents without schistosomiasis history for all groups except farmers,among them it was 8,2,12,and 8 fold higher in male,aged 40-59,workers and educational level above junior high school groups of cured schistosomiasis patients,compared with that in corresponding groups of residents without schistosomiasis history.The 95％CI of fasting plasma glucose was higher in cured schistosomiasis patients than that in residents without schistosomiasis history in most of the groups,among them the upper limits of 95％CI of fasting plasma glucose were 6.43,6.80,6.50,6.35 and 6.80 mmol/L that reached the level of IFG in the groups of female,aged 60-69,worker,illiteracy and above junior high school of cured schistosomiasis patients respectively,while the upper limits of 95％CI were within normal range in the remaining groups.Conclusion There is no significant difference for fasting plasma glucose level between cured schistosomiasis patients and normal population,however the risk of impared glucose tolerance may increase in part of the middle-aged and aged person.
